Two-Year Randomized Clinical Trial of Adjunctive Minocycline Microspheres in Periodontal Maintenance

References

1. ↵
   1. Claffey N,
   2. Nylund K,
   3. Kiger R,
   4. et al

   . Diagnostic predictability of scores of plaque, bleeding, suppuration and probing depth for probing attachment loss. 3 1/2 years of observation following initial periodontal therapy. J Clin Periodontol. 1990 Feb; 17(2):108-14.

   OpenUrlCrossRefPubMedGoogle Scholar
2. ↵
   1. Williams RC,
   2. Paquette DW,
   3. Offenbacher S,
   4. et al

   . Treatment of periodontitis by local administration of minocycline microspheres: a controlled trial. J Periodontol. 2001 Nov; 72(11): 1535-44.

   OpenUrlCrossRefPubMedWeb of ScienceGoogle Scholar
3. 1. Paquette DW,
   2. Hanlon A,
   3. Lessem J,
   4. Williams RC

   . Clinical relevance of adjunctive minocycline microspheres in patients with chronic periodontitis: secondary analysis of a phase 3 trial. J Periodontol. 2004 Apr; 75(4): 531-36.

   OpenUrlPubMedGoogle Scholar
4. ↵
   1. Lessem J,
   2. Hanlon A

   . A post-marketing study of 2805 patients treated for periodontal disease with Arestin. J Int Acad Periodontol. 2004 Oct; 6(4 suppl): 150-53.

   OpenUrlPubMedGoogle Scholar
5. ↵
   1. Oringer RJ,
   2. Al-Shammari KF,
   3. Aldredge WA,
   4. et al

   . Effect of locally delivered minocycline microspheres on markers of bone resorption. J Periodontol. 2002 Aug; 73(8): 835-42.

   OpenUrlCrossRefPubMedGoogle Scholar
6. ↵
   1. Meinberg TA,
   2. Barnes CM,
   3. Dunning DG,
   4. Reinhardt RA

   . Comparison of conventional periodontal maintenance versus scaling and root planing with subgingival minocycline. J Periodontol. 2002 Feb; 73(2): 167-72.

   OpenUrlPubMedGoogle Scholar
7. ↵
   1. van Steenberghe D,
   2. Rosling B,
   3. Söder PO,
   4. et al

   . A 15-month evaluation of the effects of repeated subgingival minocycline in chronic adult periodontitis. J Periodontol. 1999 Jun; 70(6): 657-67.

   OpenUrlCrossRefPubMedWeb of ScienceGoogle Scholar
8. ↵
   1. Payne JB,
   2. Stoner JA,
   3. Nummikoski PV,
   4. et al

   . Subantimicrobial dose doxycycline effects on alveolar bone loss in post-menopausal women. J Clin Periodontol. 2007 Sep; 34(9):776-87.

   OpenUrlCrossRefPubMedGoogle Scholar
9. ↵
   1. Killeen AC,
   2. Harn JA,
   3. Erickson LM,
   4. et al

   personKilleen AC, Harn JA, Erickson LM, et al. Local minocycline effect on inflammation and clinical attachment during periodontal maintenance: randomized clinical trial. J Periodontol. 2016 Oct; 87(10):1149-57.

   OpenUrlGoogle Scholar
10. ↵
    1. Costa FO,
    2. Cota LO,
    3. Lages EJ,
    4. et al

    . Periodontal risk assessment model in a sample of regular and irregular compliers under maintenance therapy; a 3-year prospective study. J Periodontol. 2012 Mar;83(3):292-300.

    OpenUrlCrossRefPubMedGoogle Scholar
11. ↵
    1. Navazesh M

    . Methods for collecting saliva. Ann NY Acad Sci. 1993 Sept 20; 694: 72-77.

    OpenUrlCrossRefPubMedWeb of ScienceGoogle Scholar
12. ↵
    1. Payne JB,
    2. Nummikoski PV,
    3. Thompson DM,
    4. et al

    . The association between clinical and radiographic periodontitis measurements during periodontal maintenance. J Periodontol. 2013 Oct; 84(10): 1382-1390.

    OpenUrlGoogle Scholar
13. ↵
    1. Cobb CM

    . Non-surgical pocket therapy: mechanical. Ann Periodontol. 1996 Nov; 1(1): 443-90.

    OpenUrlCrossRefPubMedGoogle Scholar
14. ↵
    1. Lang NP,
    2. Adler R,
    3. Joss A,
    4. Nyman S

    . Absence of bleeding on probing. An indicator of periodontal stability. J Clin Periodontol. 1990 Nov; 17(10): 714-21.

    OpenUrlCrossRefPubMedWeb of ScienceGoogle Scholar
15. ↵
    1. Miyamoto T,
    2. Kumagai T,
    3. Jones JA,
    4. et al

    . Compliance as a prognostic indicator: retrospective study of 505 patients treated and maintained for 15 years. J Periodontol. 2006 Feb; 77(2): 223-32.

    OpenUrlCrossRefPubMedGoogle Scholar
16. ↵
    1. Toker H,
    2. Poyraz O,
    3. Eren K

    . Effect of periodontal treatment on IL-1 beta, IL-1 ra, and IL-10 levels in gingival crevicular fluid in patients with aggressive periodontitis. J Clin Periodontol. 2008 Jun; 35(6): 507-13.

    OpenUrlCrossRefPubMedGoogle Scholar
17. ↵
    1. Kinney JS,
    2. Morelli T,
    3. Braun T,
    4. et al

    . Saliva/pathogen biomarker signatures and periodontal disease progression. J Dent Res. 2011 Aug; 90(6): 752-58.

    OpenUrlCrossRefPubMedGoogle Scholar
18. ↵
    1. Sexton WM,
    2. Lin Y,
    3. Kryscio RJ,
    4. et al

    . Salivary biomarkers of periodontal disease in response to treatment. J Clin Periodontol. 2011 May; 38(5): 434-41.

    OpenUrlCrossRefPubMedGoogle Scholar
19. ↵
    1. Rathnayake N,
    2. Akerman S,
    3. Klinge B,
    4. et al

    . Salivary biomarkers of oral health: a cross-sectional study. J Clin Periodontol. 2013 Apr 24; 40(2): 140-47.

    OpenUrlCrossRefPubMedGoogle Scholar
20. ↵
    1. Johnson GK,
    2. Guthmiller JM

    . The impact of cigarette smoking on periodontal disease and treatment. Periodontol 2000. 2007; 44: 178-94.

    OpenUrlCrossRefPubMedWeb of ScienceGoogle Scholar
21. ↵
    1. Bergström J

    . Influence of tobacco smoking on periodontal bone height. Long-term observations and a hypothesis. J Clin Periodontol. 2004 Apr; 31(4): 260-66.

    OpenUrlCrossRefPubMedWeb of ScienceGoogle Scholar
22. ↵
    1. Labriola A,
    2. Needleman I,
    3. Moles DR

    . Systematic review of the effect of smoking on nonsurgical periodontal therapy. Periodontol 2000. 2005; 37: 124-37.

    OpenUrlPubMedGoogle Scholar
23. ↵
    1. Kaldahl WB,
    2. Kalkwarf KL,
    3. Patil KD,
    4. et al

    . Long-term evaluation of periodontal therapy: I. Response to 4 modalities. J Periodontol. 1996 Feb; 67(2): 93-102.

    OpenUrlCrossRefPubMedWeb of ScienceGoogle Scholar