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Research ArticleResearch

Orofacial Manifestations of Lyme Disease: A systematic review

Brenda T. Bradshaw, Kelsey M. Jones, Joleen M. Westerdale-McInnis and Holly D. Gaff
American Dental Hygienists' Association August 2021, 95 (4) 23-31;
Brenda T. Bradshaw
Assistant professor and undergraduate program director, Gene W. Hirschfeld School of Dental Hygiene from Old Dominion University, Norfolk, VA, USA.
RDH, MSDH
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  • For correspondence: [email protected]
Kelsey M. Jones
Student in the Department of Biological Sciences from Old Dominion University, Norfolk, VA, USA.
BS
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Joleen M. Westerdale-McInnis
Librarian for the Health and Life Sciences from Old Dominion University, Norfolk, VA, USA.
MLIS, MFA
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Holly D. Gaff
Professor, Department of Biological Sciences and a honorary professor of Mathematics, Statistics and Computer Science at the University of KwaZulu-Natal, Durban, South Africa from Old Dominion University, Norfolk, VA, USA from Old Dominion University, Norfolk, VA, USA.
PhD
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References

  1. 1.↵
    1. Eisen RJ,
    2. Eisen L.
    The blacklegged tick, Ixodes scapularis: an increasing public health concern. Trends Parasitol. 2018 Apr; 34(4): 295-309.
    OpenUrlCrossRef
  2. 2.↵
    1. Centers for Disease Control and Prevention
    . Lyme disease: frequently asked questions [Internet]. Atlanta (GA); Centers for Disease Control and Prevention: 2019 [updated 2019 Sep 5; cited 2019 Oct 25]. Available from: https://www.cdc.gov/lyme/faq/
  3. 3.↵
    1. Centers for Disease Control and Prevention
    . Lyme disease [Internet]. Atlanta (GA); Centers for Disease Control and Prevention: 2019 [updated 2019 Feb 6; cited 2019 Oct 25]. Available from: http://www.cdc.gov/lyme/index.html
  4. 4.↵
    1. Centers for Disease Control and Prevention
    . Tickborne diseases of the United States: a reference manual for healthcare providers, 5th ed. [Internet]. Atlanta (GA); Centers for Disease Control and Prevention: 2019 [updated 2019 Jan 10; cited 2019 Oct 10]. Available from: https://www.cdc.gov/ticks/tickbornediseases/index.html
  5. 5.↵
    1. Centers for Disease Control and Prevention
    . Morbidity and mortality weekly report (MMWR) surveillance summaries: surveillance for Lyme disease – United States, 2008-2015; 66(22) [Internet]. Atlanta (GA); Centers for Disease Control and Prevention: 2017 [updated 2017 Nov 10; cited 2018 Nov 1]. Available from https://www.cdc.gov/mmwr/volumes/66/ss/pdfs/ss6622-H.pdf
  6. 6.↵
    1. Borchers AT,
    2. Keen CL,
    3. Huntley AC,
    4. Gershwin ME.
    Lyme disease: A rigorous review of diagnostic criteria and treatment. J Autoimmun. 2014 Feb; 2015(57): 82-115.
    OpenUrl
  7. 7.↵
    1. Lee DH,
    2. Chu PK,
    3. King B,
    4. Rosenberg D.
    Limited opening secondary to Lyme disease in an 8-year-old child. J Dent Child. 2009 Jul; 76(2): 165-9.
    OpenUrl
  8. 8.↵
    1. Avery RA,
    2. Frank, G,
    3. Glutting JJ,
    4. Eppes SC.
    Prediction of Lyme meningitis in children from a Lyme disease-endemic region: A logistic-regression model using history, physical, and laboratory findings. Pediatr. 2006 Jan; 117(1): e1-7.
    OpenUrlAbstract/FREE Full Text
  9. 9.↵
    1. Cohn KA,
    2. Thompson AD,
    3. Shah SS, et al.
    Validation of a clinical prediction rule to distinguish Lyme meningitis from aseptic meningitis. Pediatr. 2012 Jan; 129(1): e46-53.
    OpenUrlAbstract/FREE Full Text
  10. 10.↵
    1. Cook SP,
    2. Macartney KK,
    3. Rose CD, et al.
    Lyme disease and seventh nerve paralysis in children. Am J Otolaryngol. 1997 Sep-Oct; 18(5): 320-3.
    OpenUrlCrossRefPubMedWeb of Science
  11. 11.↵
    1. Dattwyler RJ,
    2. Luft BJ,
    3. Kunkel MJ, et al.
    Ceftriaxone compared with doxycycline for the treatment of acute disseminated Lyme disease. N Engl J Med. 1997 Jul; 337(5): 289-95.
    OpenUrlCrossRefPubMedWeb of Science
  12. 12.↵
    1. Gerber MA,
    2. Shapiro ED,
    3. Burke GS, et al.
    Lyme disease in children in southeastern Connecticut. N Engl J Med. 1996 Oct; 335(17): 1270-4.
    OpenUrlCrossRefPubMedWeb of Science
  13. 13.↵
    1. Nadelman RB,
    2. Nowakowski J,
    3. Forseter G, et al.
    The clinical spectrum of early Lyme borreliosis in patients with culture-confirmed erythema migrans. Am J Med. 1996 May; 100(5): 502-8.
    OpenUrlCrossRefPubMedWeb of Science
  14. 14.↵
    1. Paydar-Darian N,
    2. Kimia AA,
    3. Lantos PM, et al.
    Diagnostic lumbar puncture among children with facial palsy in a Lyme disease endemic area. JPIDS. 2017 Jun; 2017(6): 205-8.
    OpenUrl
  15. 15.↵
    1. Peltomaa M,
    2. McHugh G,
    3. Steere AC.
    The VlsE (IR6) Peptide ELISA in the serodiagnosis of Lyme facial paralysis. Otol Neurotol. 2004 Sep; 25(5): 838-41.
    OpenUrlCrossRefPubMedWeb of Science
  16. 16.↵
    1. Smouha EE,
    2. Coyle PK,
    3. Shukri S.
    Facial nerve palsy in Lyme disease: Evaluation of clinical diagnostic criteria. Am J Otol. 1997 Feb; 18(2): 257-61.
    OpenUrlPubMed
  17. 17.↵
    1. Belman AL,
    2. Coyle PK,
    3. Roque C,
    4. Cantos E.
    MRI findings in children infected by Borrelia burgdorferi. Pediatr Neurol. 1992 Jun; 8(6): 428-31.
    OpenUrlCrossRefPubMed
  18. 18.↵
    1. Liveris D,
    2. Wang G,
    3. Girao G, et al.
    Quantitative detection of Borrelia burgdorferi in 2-millimeter skin samples of erythema migrans lesions: Correlation of results with clinical and laboratory findings. J Clin Microbiol. 2002 Apr; 40(4): 1249-53.
    OpenUrlAbstract/FREE Full Text
  19. 19.↵
    1. Jain VK,
    2. Hilton E,
    3. Maytal J, et al.
    Immunoglobulin M immunoblot for diagnosis of Borrelia burgdorferi infection in patients with acute facial palsy. J Clin Microbiol. 1996 Aug; 34(8): 2033-5.
    OpenUrlAbstract/FREE Full Text
  20. 20.↵
    1. Brett ME,
    2. Hinckley AF,
    3. Zielinski-Gutierrez EC,
    4. Mead PS.
    US healthcare providers’ experience with Lyme and other tick-borne diseases. Ticks Tick Borne Dis. 2014 Jun; 5(4): 404-8.
    OpenUrlCrossRefPubMed
  21. 21.↵
    1. US Department of Health and Human Services
    . Tick-borne disease working group: 2018 report to congress [Internet]. Washington (DC); US Department of Health and Human Services: 2018 [updated 2018; cited 2019 Oct 10]. Available from: https://www.hhs.gov/sites/default/files/tbdwg-report-to-congress-2018.pdf
  22. 22.↵
    1. Moher D,
    2. Liberati A,
    3. Tetzlaff J,
    4. Altman DG.
    Preferred reporting items for systematic reviews and meta-analyses: The PRISMA statement. BMJ. 2009 Aug; 339(7): 332-336. Available from: https://www.jstor.org/stable/25672329?seq=1&cid=pdf-reference#references_tab_contents
    OpenUrlCrossRef
  23. 23.↵
    1. National Library of Medicine
    . Unified Medical Language System (UMLS) [Internet]. Bethesda (MD): National Institutes of Health; 2019 [updated 2019 May 23; cited 2019 Feb 1]. Available from: https://www.nlm.nih.gov/research/umls/index.html
  24. 24.↵
    1. Goldfarb D,
    2. Sataloff RT.
    Lyme disease: A review for the otolaryngologist. Ear Nose Throat J. 1994 Nov; 73(11): 824-9.
    OpenUrlPubMed
  25. 25.
    1. Haney C,
    2. Nahata MC.
    Unique expression of chronic Lyme disease and Jarisch-Herxheimer reaction to doxycycline therapy in a young adult. BMJ Case Rep. 2016 Jul; doi: 10.1136/bcr-2013-009433.
    OpenUrlAbstract/FREE Full Text
  26. 26.
    1. Heir GM.
    Differentiation of orofacial pain related to Lyme disease from other dental and facial pain disorders. Dent Clin North Am. 1997; 41(2): 243-58.
    OpenUrlPubMed
  27. 27.
    1. Heir GM,
    2. Fein LA.
    Lyme disease awareness for the New Jersey dentist: A survey of orofacial and headache complaints associated with Lyme disease. J N J Dent Assoc. 1997 Dec; 69(1): 19, 21, 62-3, 69.
    OpenUrl
  28. 28.
    1. Heir GM,
    2. Fein LA.
    Lyme disease: Considerations for dentistry. J Orofac Pain. 1996 Win; 10(1): 74-86.
    OpenUrlPubMed
  29. 29.
    1. Emkey GR,
    2. Stone JH.
    A 46-year old woman with chin pain and a fainting spell. Arthritis Care Res. 2010 Mar; 62(3): 434-8.
    OpenUrl
  30. 30.
    1. Halperin JJ.
    Is neuroborresliosis a medical emergency? Neurocrit Care. 2006 Jun; 2006(4): 260-6.
    OpenUrl
  31. 31.
    1. Halperin JJ.
    Nervous system Lyme disease. Infect Dis Clin N Am. 2008 Jun; 22(2): 261-74.
    OpenUrlCrossRefPubMedWeb of Science
  32. 32.
    1. Greer DM,
    2. Schaefer PW,
    3. Plotkin SR, et al.
    Case 11-2007: A 59-year old man with neck pain, weakness in the arms, and cranial-nerve palsies. N Engl J Med. 2007 Apr; 356(15): 1561-70.
    OpenUrlCrossRefPubMedWeb of Science
  33. 33.
    1. Greenberg MR,
    2. Urquhart MC,
    3. Eygnor JK, et al.
    I can’t move my face! A case of bilateral facial palsy. J Am Osteopath Assoc. 2013 Oct; 113(10): 788-90.
    OpenUrlCrossRefPubMed
  34. 34.↵
    1. Glickstein L,
    2. Moore B,
    3. Bledsoe T, et al.
    Inflammatory cytokine production predominates in early Lyme disease in patients with erythema migrans. Infect Immun. 2003 Oct; 71(10): 6051-3.
    OpenUrlAbstract/FREE Full Text
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August 2021
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Orofacial Manifestations of Lyme Disease: A systematic review
Brenda T. Bradshaw, Kelsey M. Jones, Joleen M. Westerdale-McInnis, Holly D. Gaff
American Dental Hygienists' Association Aug 2021, 95 (4) 23-31;

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Orofacial Manifestations of Lyme Disease: A systematic review
Brenda T. Bradshaw, Kelsey M. Jones, Joleen M. Westerdale-McInnis, Holly D. Gaff
American Dental Hygienists' Association Aug 2021, 95 (4) 23-31;
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Keywords

  • Lyme disease
  • orofacial manifestations
  • oral care
  • dental hygienists
  • oral health care providers
  • systematic review

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