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Research ArticleShort Report

Treatment Modalities for Drug–Induced Gingival Enlargement

Michelle Moffitt, Davide Bencivenni and Robert Cohen
American Dental Hygienists' Association September 2012, 86 (4) 272-277;
Michelle Moffitt
RDH
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Davide Bencivenni
DDS, MS
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Robert Cohen
DDS, PhD
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  • Article
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References

    1. Doufexi A,
    2. Mina M,
    3. Ioannidou E
    . Gingival Overgrowth in Children: Epidemiology, Pathogenesis, and Complications. J Periodontol. 2005;76(1):4-10.
    OpenUrl
    1. Grant MM,
    2. Kolamunne RT,
    3. Lock FE,
    4. Matthews JB,
    5. Chapple IL,
    6. Griffiths HR
    . Oxygen tension modulates the cytokine response of oral epithelium to periodontal bacteria. J Clin Periodontol. 2010;37(12):1039-1048.
    OpenUrlCrossRefPubMed
    1. Page RC
    . The role of inflammatory mediators in the pathogenesis of periodontal disease. J Periodontal Res. 1991;26(3 Pt 2):230-242.
    OpenUrlCrossRefPubMedWeb of Science
    1. Dongari-Bagtzoglou A
    ; Research, Science and Therapy Committee, American Academy of Periodontology. Drug-associated gingival enlargement. J Periodontol. 2004;75(10):1424-1431.
    OpenUrlPubMed
    1. Dannewitz B
    . Proliferation of the gingiva: aetiology, risk factors and treatment modalities for gingival enlargement. Perio. 2007;4(2):83-91.
    OpenUrl
    1. Bolger WE,
    2. West CB Jr.,
    3. Parsons DS,
    4. Gates GA
    . Upper airway obstruction due to massive gingival hyperplasia. A case report and description of a new surgical technique. Int J Pediatr Otorhinolaryngol. 1990;19(1):63-72.
    OpenUrlPubMed
  1. Parameters of Care. J Periodontol. 2000;71(Suppl 5):847-883.
    OpenUrlPubMed
    1. Camargo PM,
    2. Melnick PR,
    3. Pirih FQ,
    4. Lagos R,
    5. Takei HH
    . Treatment of drug-induced gingival enlargement: aesthetic and functional considerations. Periodontol 2000. 2001;27:131-138.
    OpenUrlPubMed
    1. Dongari A,
    2. McDonnel HT,
    3. Langlais RP
    . Drug-induced gingival overgrowth. Oral Surg Oral Med Oral Pathol. 1993;76(4):543-548.
    OpenUrlCrossRefPubMed
    1. Axelsson P,
    2. Lindhe J
    . Effect of controlled oral hygiene procedures on caries and periodontal disease in adults. Results after 6 years. J Clin Periodontol. 1981;8(3):239-248.
    OpenUrlCrossRefPubMed
    1. Ilgenli T,
    2. Atilla G,
    3. Baylas H
    . Effectiveness of periodontal therapy in patients with drug-induced gingival overgrowth. Long-term results. J Periodontol. 1999;70(9):967-972.
    OpenUrlPubMed
  2. Research, Science and Therapy Committee of the American Academy of Periodontology. Treatment of plague-induced gingivitis, chronic periodontitis, and other clinical conditions. J Periodontol. 2001;72(12):1790-1800.
    OpenUrlCrossRefPubMedWeb of Science
    1. Babcock JR
    . The successful use of new therapy for Dilantin gingival hyperplasia. Periodontics. 1965;149:196-199.
    OpenUrlPubMed
    1. Pilatti GL,
    2. Sampaio JE
    . The influence of chlorexidine in the severity of cyclosporin A-induced gingival overgrowth. J Periodontol. 1997;68(9):900-904.
    OpenUrlPubMedWeb of Science
    1. Cohen RE
    . Research, Science and Therapy Committee, American Academy of Periodontology. Position paper periodontal maintenance. J Periodontol. 2003;74(9):1395-1401.
    OpenUrlPubMed
    1. Santi E,
    2. Bral M
    . Effect of treatment on cyclosporine- and nifedipine-induced gingival enlargement: clinical and histologic results. Int J Periodontics Restorative Dent. 1998;18(1):80-85.
    OpenUrlPubMed
    1. Rossmann JA,
    2. Ingles E,
    3. Brown RS
    . Multimodal treatment of drug-induced gingival hyperplasia in a kidney transplant patient. Compendium. 1994;15(10):1266, 1268-1270, 1272-1274.
    OpenUrlPubMed
    1. Wahlstrom E,
    2. Zamora JU,
    3. Teichman S
    . Improvement in cyclosporine-associated gingival hyperplasia with azithromycin therapy. N Engl J Med. 1995;332(11):753-754.
    OpenUrlCrossRefPubMed
    1. Wong W,
    2. Hodge MG,
    3. Lewis A,
    4. Sharpstone P,
    5. Kingswood JC
    . Resolution of cyclosporin-induced gingival overgrowth with metronidazole. Lancet. 1994;343(8903):989.
    OpenUrlPubMed
    1. Jugclà A,
    2. Moreso F,
    3. Sais G,
    4. et al
    . The use of azythromycin for cyclosporine-induced gingival overgrowth. Br J Dermatol. 1998;138(1):198-199.
    OpenUrlPubMed
    1. Hassell TM,
    2. Hefti AF
    . Drug-induced gingival overgrowth: old problem, new problem. Crit Rev Oral Biol Med. 1991;2(1):103-107.
    OpenUrlFREE Full Text
    1. Kantarci A,
    2. Cebeci I,
    3. Tuncer O,
    4. Carin M,
    5. Firatli E
    . Clinical effects of periodontal therapy on the severity of cyclosporin-A-induced gingival hyperplasia. J Periodontol. 1999;70(6):587-593.
    OpenUrlCrossRefPubMedWeb of Science
    1. Gómez E,
    2. Sánchez-Nuńez M,
    3. Sánches JE,
    4. et al
    . Treatment of cyclosporin-induced gingival hyperplasia with azithromycin. Nephrol Dial Transplant. 1997;12(12):2694-2697.
    OpenUrlAbstract/FREE Full Text
    1. Nowicki M,
    2. Kokot F,
    3. Wiecek A
    . Partial regression of advanced cyclosporin-induced gingival hyperplasia after treatment with azithromycin. A case report. Ann Transplant. 1998;3(3):25-27.
    OpenUrlPubMed
    1. Aufricht C,
    2. Hogan EL,
    3. Ettenger RB
    . Oral metronidazole does not improve cyclosporin A-induced gingival hyperplasia. Pediatr Nephrol. 1997;11(5):525-555.
    OpenUrl
    1. Mesa FL,
    2. Osuna A,
    3. Aneiros J,
    4. et al
    . Antibiotic treatment of incipient drug-induced gingival overgrowth in adult renal transplant patients. J Periodontal Res. 2003;38(2):141-146.
    OpenUrlPubMed
    1. Dahllöf G,
    2. Preber H,
    3. Eliasson S,
    4. Rydén H,
    5. Karsten J,
    6. Modéer T
    . Periodontal conditions of epileptic adults treated long-term with phenytoin or carbamazepine. Epilepsia. 1993;34(5):960-964.
    OpenUrlPubMed
    1. Anderson HH,
    2. Rapley JW,
    3. Williams DR
    . Gingival overgrowth with valproic acid: a case report. ASDC J Dent Child. 1997;64(4):294-297.
    OpenUrlPubMed
    1. Hernández G,
    2. Arriba L,
    3. Lucas M,
    4. de Andrés A
    . Reduction of severe gingival overgrowth in a kidney transplant patient by replacing cyclosporin A with tacrolimus. J Periodontol. 2000;71(10):1630-1636.
    OpenUrlPubMedWeb of Science
    1. Fattore L,
    2. Stablein M,
    3. Bredfeldt G,
    4. Semla T,
    5. Moran M,
    6. Doherty-Greenberg JM
    . Gingival hyperplasia: a side-effect of nifedipine and diltiazem. Spec Care Dentist. 1991;11(3):107-109.
    OpenUrlCrossRefPubMed
  3. Dental Therapeutics. 2nd ed. Chicago: ADA Publishing Company; 2001.
    1. Colombo AP,
    2. Boches SK,
    3. Cotton SL,
    4. et al
    . Comparisons of subgingival microbial profiles of refractory periodontitis, severe periodontitis, and periodontal health using the human oral microbe identification microarray. J Periodontol. 2009;80(9):1421-1432.
    OpenUrlCrossRefPubMedWeb of Science
    1. Mattson JS,
    2. Blankenau R,
    3. Keene JJ
    . Case Report. Use of an argon laser to treat drug-induced gingival overgrowth. J Am Dent Assoc. 1998;129(1):78-83.
    OpenUrlAbstract/FREE Full Text
    1. Guelmaan M,
    2. Britto LR,
    3. Katz J
    . Cyclosporin-induced gingival overgrowth treated with CO2 laser: a case report. J Clin Pediatr Dent. 2003;27(2):123-126.
    OpenUrlPubMed
    1. Roed-Petersen B
    . The potential use of CO2 laser gingivectomy for phenytoin-induced gingival hyperplasia in mentally retarded patients. J Clin Periodontol. 1993;20(10):729-731.
    OpenUrlPubMed
    1. Barak S,
    2. Katz J,
    3. Kaplan I
    . The CO2 laser in surgery of vascular tumors of the oral cavity in children. ASDC J Dent Child. 1991;58(4):293-296.
    OpenUrlPubMed
    1. Convissar RA,
    2. Diamond LB,
    3. Fazekas CD
    . Laser treatment of orthodontically induced gingival hyperplasia. Gen Dent. 1996;44(1):47-51.
    OpenUrlPubMed
    1. Pilloni A,
    2. Camargo PM,
    3. Carere M,
    4. Carranza FA Jr.
    . Surgical treatment of cyclosporin A- and nifedipine-induced gingival enlargement: gingivectomy versus periodontal flap. J Periodontol. 1998;69(7):791-797.
    OpenUrlPubMed
    1. Saravia ME,
    2. Svirsky JA,
    3. Friedman R
    . Chlorexidine as an oral hygiene adjunct for cyclosporine-induced gingival hyperplasia. ASDC J Dent Child. 1990;57(5):366-370.
    OpenUrlPubMed
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American Dental Hygienists Association: 86 (4)
American Dental Hygienists' Association
Vol. 86, Issue 4
Fall 2012
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Treatment Modalities for Drug–Induced Gingival Enlargement
Michelle Moffitt, Davide Bencivenni, Robert Cohen
American Dental Hygienists' Association Sep 2012, 86 (4) 272-277;

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Treatment Modalities for Drug–Induced Gingival Enlargement
Michelle Moffitt, Davide Bencivenni, Robert Cohen
American Dental Hygienists' Association Sep 2012, 86 (4) 272-277;
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