Activation of Raf as a result of recruitment to the plasma membrane

D Stokoe, SG Macdonald, K Cadwallader, M Symons… - Science, 1994 - science.org
The small guanine nucleotide binding protein Ras participates in a growth promoting signal
transduction pathway. The mechanism by which interaction of Ras with the protein kinase …

[HTML][HTML] Phase I study of the intravenous administration of attenuated Salmonella typhimurium to patients with metastatic melanoma

…, S Mavroukakis, D White, S MacDonald… - Journal of clinical …, 2002 - ncbi.nlm.nih.gov
Results The maximum-tolerated dose was 3× 10 8 cfu/m². Dose-limiting toxicity was observed
in patients receiving 1× 10 9 cfu/m², which included thrombocytopenia, anemia, persistent …

[BOOK][B] Professional academic writing in the humanities and social sciences

SP MacDonald - 2010 - books.google.com
… Social Sciences, Susan Peck MacDonald tackles important and … MacDonald argues that
the academy has devoted more … Throughout the book, MacDonald stresses her conviction that …

[HTML][HTML] Pragmatic controlled clinical trials in primary care: the struggle between external and internal validity

M Godwin, L Ruhland, I Casson, S MacDonald… - BMC medical research …, 2003 - Springer
Background Controlled clinical trials of health care interventions are either explanatory or
pragmatic. Explanatory trials test whether an intervention is efficacious; that is, whether it can …

Molecular identification of an IgE-dependent histamine-releasing factor

SM MacDonald, T Rafnar, J Langdon, LM Lichtenstein - Science, 1995 - science.org
An immunoglobulin E (IgE)-dependent histamine-releasing factor (HRF) produced by
lymphocytes of atopic children and present in biological fluids of allergic patients has been …

Binding of 14-3-3 proteins to the protein kinase Raf and effects on its activation

E Freed, M Symons, SG Macdonald, F McCormick… - Science, 1994 - science.org
To identify proteins that may participate in the activation of the protein kinase Raf, proteins that
interact with Raf were selected in a two-hybrid screen. Two members of the 14-3-3 protein …

Mycotoxin analysis: An update

…, A Molinelli, M Sulyok, S MacDonald… - Food additives and …, 2008 - Taylor & Francis
Mycotoxin contamination of cereals and related products used for feed can cause intoxication,
especially in farm animals. Therefore, efficient analytical tools for the qualitative and …

Career development for women in academic medicine: Multiple interventions in a department of medicine

LP Fried, CA Francomano, SM MacDonald… - Jama, 1996 - jamanetwork.com
Objective. —To determine the gender-based career obstacles for women in an academic
department of medicine and to report the interventions to correct such obstacles (resulting from …

Comparative Study of Carbon Dioxide Reforming of Methane to Synthesis Gas over Ni/La2O3 and Conventional Nickel-Based Catalysts

Z Zhang, XE Verykios, SM MacDonald… - The Journal of …, 1996 - ACS Publications
Carbon dioxide reforming of methane to synthesis gas was studied by employing a Ni/La 2 O
3 catalyst as well as conventional nickel-based catalysts, ie, Ni/γ-Al 2 O 3 , Ni/CaO/γ-Al 2 O …

Protein kinase A antagonizes platelet-derived growth factor-induced signaling by mitogen-activated protein kinase in human arterial smooth muscle cells.

…, EW Raines, BC Potts, SG Macdonald… - Proceedings of the …, 1993 - National Acad Sciences
Stimulation of aortic smooth muscle cells with platelet-derived growth factor BB homodimer (PDGF-BB)
leads to the rapid activation of mitogen-activated protein kinase (MAPK) and …