User profiles for S. Zakynthinos

Spyros Zakynthinos

Professor of Medicine, National and Kapodistrian University of Athens
Verified email at med.uoa.gr
Cited by 12496

Respiratory muscles and weaning failure

T Vassilakopoulos, S Zakynthinos… - European Respiratory …, 1996 - Eur Respiratory Soc
Weaning failure is, unfortunately, a rather common phenomenon for mechanically-ventilated
patients (especially those with chronic obstructive pulmonary disease (COPD)), and the …

[HTML][HTML] Nasal high flow therapy: a novel treatment rather than a more expensive oxygen device

…, I Pantazopoulos, S Zakynthinos - European Respiratory …, 2017 - Eur Respiratory Soc
… (S pO 2 , respiratory rate and forced expiratory volume in 1 s) and cardiovascular (systolic
and diastolic arterial pressure and heart rate) variables did not differ between groups. Positive …

Factors limiting exercise tolerance in chronic lung diseases

I Vogiatzis, S Zakynthinos - Comprehensive Physiology, 2012 - Wiley Online Library
The major limitation to exercise performance in patients with chronic lung diseases is an
issue of great importance since identifying the factors that prevent these patients from carrying …

Vasopressin, steroids, and epinephrine and neurologically favorable survival after in-hospital cardiac arrest: a randomized clinical trial

…, E Zakynthinos, E Zintzaras, S Sourlas, S Aloizos… - Jama, 2013 - jamanetwork.com
… The present study’s experimental VSE-CPR regimen included methylprednisolone, which
may enhance the vasopressor effects of vasopressin 28 and epinephrine. As periarrest …

The tension–time index and the frequency/tidal volume ratio are the major pathophysiologic determinants of weaning failure and success

T Vassilakopoulos, S Zakynthinos… - American journal of …, 1998 - atsjournals.org
… Compared with S, during F patients had greater intrinsic positive end-expiratory pressure (…
4.95 versus 11.19 ± 4.01 cm H 2 O/L/s), ratio of mean to maximum inspiratory pressure (0.46 ± …

Coagulation system and platelets are fully activated in uncomplicated sepsis

…, V Christopoulou-Kokkinou, S Zakynthinos - Critical care …, 2000 - journals.lww.com
… For determination of prothrombin time, calcium-thromboplastin of human placental origin (Thrombogel
S, Behring) was added to citrated plasma and the result was expressed in …

Angiopoietin-2 is increased in severe sepsis: correlation with inflammatory mediators

…, C Sotiropoulou, S Zakynthinos… - Critical care …, 2007 - journals.lww.com
… Spearman rank correlation coefficients (r s ) were calculated to describe the … s = −0.280, p
< .05) but did not correlate with chest roentgenogram score (r s = 0.269), lung injury score (r s

Skeletal muscle adaptations to interval training in patients with advanced COPD

…, DCM Simoes, O Georgiadou, S Zakynthinos… - Chest, 2005 - Elsevier
… ]) with 30-s work periods interspersed with 30-s rest periods for 45 min/d. Patients (n = 9)
allocated to CLE training exercised at a mean intensity of 75 ± 5% Wpeak for 30 min/d. Patients …

Vasopressin, epinephrine, and corticosteroids for in-hospital cardiac arrest

SD Mentzelopoulos, SG Zakynthinos… - Archives of internal …, 2009 - jamanetwork.com
… Dr Mentzelopoulos was the principal investigator; Dr Zakynthinos, the study director; and
Dr Roussos, the study chair. Study concept: Mentzelopoulos. Study design: Mentzelopoulos, …

Prone position reduces lung stress and strain in severe acute respiratory distress syndrome

…, C Roussos, SG Zakynthinos - European Respiratory …, 2005 - Eur Respiratory Soc
… V T s (0.6 L = 9.0±0.9 mL·kg −1 PBW) 9, 39–42 in prone/SR PP is equally protective as
ventilation with low V T s (… Consequently, if in severe ARDS, low V T s are accepted as the “gold …