During the past decade we and others have shown that bone is a storehouse for growth
factors. Accordingly, bone contains a number of growth factors including insulin‐like growth …

Platelet‐derived growth factor (PDGF) and insulin‐like growth factor I (IGF‐I) in combination
have previously been shown to enhance periodontal regeneration. The objective of this …

Human bone matrix is known to contain a battery of polypeptide growth factors. Since dentin
is a mineralized tissue similar to bone in composition and perhaps in formation, human …

The present studies evaluated the efficacy of a controlled‐release biodegradable Chlorhexidine
(CHX) (2.5 mg) chip when used as an adjunct to scaling and root planing on reducing …

Two commonly used animal models for evaluating putative periodontal regenerative therapies
are the beagle dog model with natural periodontal disease and the non‐human primate …

New aspects of the distribution and developmental appearance of the 44-kDa bone
phosphoprotein (44K BPP, also called sialoprotein I or osteopontin) and bone γ-carboxyglutamic …

Context: Polycystic ovary syndrome (PCOS), the most common endocrinopathy in women, is
characterized by high secretion levels of LH and T. Currently, there is no treatment licensed …

Platelet‐derived growth factor (PDGF), an osteoblast mitogen, has been demonstrated to
accelerate fracture healing and periodontal bone repair when applied locally in vivo. To …

Src is a nonreceptor tyrosine kinase thought to be essential for osteoclast function and bone
resorption. We investigated the effect of the orally available Src inhibitor saracatinib (…

Given potential differences between the skeletal and other effects of the third generation
aromatase inhibitors (AIs), we conducted an open, randomised Phase I study, comparing the …