The endocrine hormone fibroblast growth factor 21 (FGF21) is a powerful modulator of glucose
and lipid metabolism and a promising drug for type 2 diabetes. Here we identify FGF21 …

The influence of elastic properties on finite‐element analysis was investigated using a finite‐element
model of a Macaca fascicularis skull. Four finite‐element analyses were performed …

This article reviews the fundamental principles of the finite element method and the three
basic steps (model creation, solution, and validation and interpretation) involved in using it to …

Cephalometric radiographs from a sample of 64 untreated persons (32 Class I and 32 Class
II) were evaluated to determine the amount, direction and timing of facial soft tissue …

The African Plio-Pleistocene hominins known as australopiths evolved a distinctive craniofacial
morphology that traditionally has been viewed as a dietary adaptation for feeding on …

The material properties of cortical bone from the diaphyses of long bones (eg, the femur and
tibia) vary by direction, such that bone is stiffer and stronger along its long axis. This …

Long-term usage of rosiglitazone, a synthetic PPARγ agonist, increases fracture rates
among diabetic patients. PPARγ suppresses osteoblastogenesis while activating …

… (Dechow et al., 1992 and the current study) indicate that on average E, is approximately 40%
larger than E,.l Preliminary studies in our laboratory on the macaque mandible (Dechow et …

Wnt/β-catenin signaling is a critical regulator of skeletal physiology. However, previous studies
have mainly focused on its roles in osteoblasts, while its specific function in osteoclasts is …

The aim of this study was to determine regional variability of material properties in the
dentate maxilla. Cortical samples were removed from 15 sites of 15 adult dentate fresh‐frozen …