A major superfamily of transmembrane facilitators that catalyse uniport, symport and antiport

MD Marger, MH Saier Jr - Trends in biochemical sciences, 1993 - Elsevier
Many transport proteins of bacteria and eukaryotes are thought to possess a common structural
motif of 12 transmembrane-spanning α-helical segments. In this report we use statistical …

Therapeutic potential of α7 nicotinic acetylcholine receptors

D Bertrand, CHL Lee, D Flood, F Marger… - Pharmacological …, 2015 - ASPET
Progress in the fields of neuroscience and molecular biology has identified the forebrain
cholinergic system as being important in many higher order brain functions. Further analysis of …

Zinc: an underappreciated modulatory factor of brain function

L Marger, CR Schubert, D Bertrand - Biochemical pharmacology, 2014 - Elsevier
… Studies of different LGIC types revealed a common pattern of function with extrasynaptic
receptors generally displaying a higher sensitivity to agonists and lesser propensity for …

Control of heart rate by cAMP sensitivity of HCN channels

J Alig, L Marger, P Mesirca, H Ehmke… - Proceedings of the …, 2009 - National Acad Sciences
… Our data also reveal the pathophysiologic mechanism of hHCN4–573X–linked SAN …
Seeburg and R. Sprengel for the Tet system indicator mice and the International Research Institute …

Are nonspecific practice guidelines potentially harmful? A randomized comparison of the effect of nonspecific versus specific guidelines on physician decision making.

PG Shekelle, RL Kravitz, J Beart, M Marger… - Health services …, 2000 - ncbi.nlm.nih.gov
… Examination by your colleague at that time revealed a positive straight leg raising test and
a normal neurologic examination. Plain x-ray of the lumbar spine was normal and a CT scan …

Testing tooth brushing ability of elderly patients

R Felder, M Reveal, S Lemon… - Special Care in …, 1994 - Wiley Online Library
… (r = 0.719; p < 0.000). Correlations also revealed high interrater (r = 0.87) and intrarater
reliability ( r = … Crosssectional studies reveal increasing plaque and gingivitis levels with age in …

Dexterity testing as a predictor of oral care ability

…, C Brown, S Lemon, M Reveal - Journal of the …, 1994 - Wiley Online Library
revealed significant correlations ranging in absolute value from r s = 0.402 (P = 0.003) for Grip
Strength to r … , and Box and Block tests were in the r s = ± 0.5 range, suggesting significant …

T-type calcium channels contribute to colonic hypersensitivity in a rat model of irritable bowel syndrome

F Marger, A Gelot, A Alloui, J Matricon… - Proceedings of the …, 2011 - National Acad Sciences
… This analysis revealed that the increase in T-type current density began within 3 h after
butyrate application and was nearly maximal by ∼12 h (Fig. 6A). We subsequently tested …

Dithiol amino acids can structurally shape and enhance the ligand-binding properties of polypeptides

…, R Gopalakrishnan, T Schaer, F Marger, R Hovius… - Nature …, 2014 - nature.com
… The measurements revealed that the improvement in binding of both Dtaa-containing bicyclic
peptides resulted from larger enthalpy changes. The enthalpy effects were partially offset …

Origin of Monte Rosa whiteschist from in-situ tourmaline and quartz oxygen isotope analysis by SIMS using new tourmaline reference materials

K Marger, C Luisier… - … : Journal of Earth …, 2019 - pubs.geoscienceworld.org
… The core reveals similar chemical composition and zonation as meta-leucogranitic …
Oxygen isotope data reveal homogeneous composition for metagranite and meta-leucogranite …