Human serum albumin (HSA) has been used for a long time as a resuscitation fluid in
critically ill patients. It is known to exert several important physiological and pharmacological …

Intensive Care Unit (ICU) patients almost uniformly suffer from sleep disruption. Even though
the role of sleep disturbances is not still adequately understood, they may be related to …

CE‐ and microchip‐based separations coupled with LIF are powerful tools for the separation,
detection and determination of biomolecules. CE with certain configurations has the …

Alteration of brain aerobic glycolysis is often observed early in the course of Alzheimer's
disease (AD). Whether and how such metabolic dysregulation contributes to both synaptic …

We have demonstrated that the polyethylene glycol (PEG) corona of long-circulating polymeric
nanoparticles (NPs) favors interaction with the amyloid-beta (Aβ 1–42 ) peptide both in …

Previous in vivo observations in rats have shown that poly(ethylene glycol)
polyhexadecylcyanoacrylate (PEG-PHDCA) nanoparticles could translocate into the brain after …

… This buffer was prepared by mixing appropriate volumes of stock solutions of phosphoric
acid (1 M), boric acid (1 M) and sodium hydroxide (1M). All electrolyte pHs were checked with …

Objective The metabolic syndrome (MS) is a cluster of cardiometabolic factors, which predisposes
to diabetes and cardiovascular disease (CVD). Early detection of high-risk individuals …

Background. Critically ill patients suffer from physiological sleep deprivation and have
reduced blood melatonin levels. This study was designed to determine whether nocturnal …

Critically ill patients exhibit reduced melatonin secretion, both in nocturnal peaks and basal
daytime levels. Oral melatonin supplementation may be useful for known sedative and …