Perturbations to the well-being of tissues in plants and invertebrates generate fragments of
endogenous molecules that are recognized by innate immune receptors. Vertebrates have …

BACKGROUND & AIMS: The ability to obtain unlimited numbers of human hepatocytes would
improve the development of cell-based therapies for liver diseases, facilitate the study of …

… In this paper Jeffrey Platt, Fritz Bach and colleagues describe a model of hyperacute .rejection
and propose that, if 5yperacute rejection can b~ averted for a period after transp/dntation, …

Hyperacute rejection is the inevitable consequence of the transplantation of vascularized
organs between phylogenetically distant species. The nature of the incompatibility and the …

The susceptibility of xenografts to hyperacute rejection is postulated to reflect in part failure
of complement regulatory proteins (CRPs) to control activation of heterologous complement …

The aim of this paper was to review in vitro and in situ studies that directly compared the use
of bovine teeth as a substitute for human teeth in dental experiments. A PubMed search was …

BACKGROUND: The problem of AMR remains unsolved because standardized schemes
for diagnosis and treatment remains contentious. Therefore, a consensus conference was …

Until recently, cells were thought to be integral and discrete components of tissues, and their
state was determined by cell differentiation. However, under some conditions, stem cells or …

The process of humoral rejection is multifaceted and has different manifestations in the various
types of organ transplants. Because this process is emerging as a leading cause of graft …

Background. Thechronic shortage in the supply of human organs available for allotransplantation
has turned attention toward the use of animals as potential donors, with pigs as the …