Porphyromonas gingivalis, the keystone pathogen in chronic periodontitis, was identified in
the brain of Alzheimer’s disease patients. Toxic proteases from the bacterium called …

The pathogenesis of periodontitis involves a complex immune/inflammatory cascade that is
initiated by the bacteria of the oral biofilm that forms naturally on the teeth. The susceptibility …

Inflammation is a complex reaction to injurious agents and includes vascular responses,
migration, and activation of leukocytes. Inflammation starts with an acute reaction, which …

Background: Platelet‐rich plasma (PRP) promotes regeneration of bone, presumably through
the action of concentrated growth factors. However, it is not clear how PRP affects the …

Background: This study compared the subgingival microbiota of subjects with refractory
periodontitis (RP) to those in subjects with treatable periodontitis (GRs = good responders) or …

Age is a non-modifiable risk factor for the inflammation that underlies age-associated diseases;
thus, anti-inflammaging drugs hold promise for increasing health span. Cytokine profiling …

Resolvin E1 (RvE1) is a potent proresolving mediator of inflammation derived from omega-3
eicosapentaenoic acid that acts locally to stop leukocyte recruitment and promote resolution…

The oral microbiome, the complex ecosystem of microbes inhabiting the human mouth, harbors
several thousands of bacterial types. The proliferation of pathogenic bacteria within the …

An appropriate balance between proinflammatory (Th17 and Th1) and anti-inflammatory (regulatory
T cells [Tregs] and Th2) subsets of T cells is critical to maintain homeostasis and …

Diabetes mellitus is a group of metabolic disorders with high mortality and morbidity associated
with complications such as cardiovascular disease, kidney disease, and stroke. The …