[HTML][HTML] Prompt plasma exchanges and immunosuppressive treatment improves the outcomes of anti-factor H autoantibody-associated hemolytic uremic syndrome in …
Antibodies to complement factor H are an uncommon cause of hemolytic uremic syndrome (HUS).
Information on clinical features and outcomes in children is limited. In order to explore …
Information on clinical features and outcomes in children is limited. In order to explore …
[HTML][HTML] ACE2 protein expression in lung tissues of severe COVID-19 infection
…, A Trikha, S Arava, P Das, AR Mridha, G Singh… - Scientific reports, 2022 - nature.com
Angiotensin-converting enzyme 2 (ACE2) is a key host protein by which severe acute respiratory
syndrome coronavirus-2 (SARS-CoV-2) enters and multiplies within cells. The level of …
syndrome coronavirus-2 (SARS-CoV-2) enters and multiplies within cells. The level of …
Novel selective agents for the degradation of androgen receptor variants to treat castration-resistant prostate cancer
Androgen receptor (AR) mediates the growth of prostate cancer throughout its course of
development, including in abnormal splice variants (AR-SV)-driven advanced stage castration-…
development, including in abnormal splice variants (AR-SV)-driven advanced stage castration-…
[HTML][HTML] A systematic review of time series classification techniques used in biomedical applications
…, I Chen, L Hershkovich, J Yang, A Shetty, G Singh… - Sensors, 2022 - mdpi.com
Background: Digital clinical measures collected via various digital sensing technologies
such as smartphones, smartwatches, wearables, and ingestible and implantable sensors are …
such as smartphones, smartwatches, wearables, and ingestible and implantable sensors are …
[HTML][HTML] Structural basis of BAK activation in mitochondrial apoptosis initiation
G Singh, CD Guibao, J Seetharaman… - Nature …, 2022 - nature.com
BCL-2 proteins regulate mitochondrial poration in apoptosis initiation. How the pore-forming
BCL-2 Effector BAK is activated remains incompletely understood mechanistically. Here we …
BCL-2 Effector BAK is activated remains incompletely understood mechanistically. Here we …
[HTML][HTML] Demographic imbalances resulting from the bring-your-own-device study design
…, Y Dinh, A Patil, L Martin, G Singh… - JMIR mHealth and …, 2022 - mhealth.jmir.org
Digital health technologies, such as smartphones and wearable devices, promise to
revolutionize disease prevention, detection, and treatment. Recently, there has been a surge of …
revolutionize disease prevention, detection, and treatment. Recently, there has been a surge of …
[HTML][HTML] Transient receptor potential channel 6 (TRPC6) protects podocytes during complement-mediated glomerular disease
AD Kistler, G Singh, MM Altintas, H Yu… - Journal of Biological …, 2013 - ASBMB
Gain-of-function mutations in the calcium channel TRPC6 lead to autosomal dominant focal
segmental glomerulosclerosis and podocyte expression of TRPC6 is increased in some …
segmental glomerulosclerosis and podocyte expression of TRPC6 is increased in some …
Genome-wide distribution of macroH2A1 histone variants in mouse liver chromatin
LN Changolkar, G Singh, K Cui… - … and cellular biology, 2010 - Taylor & Francis
Studies of macroH2A histone variants indicate that they have a role in regulating gene
expression. To identify direct targets of the macroH2A1 variants, we produced a genome-wide …
expression. To identify direct targets of the macroH2A1 variants, we produced a genome-wide …
[HTML][HTML] Renal detection of Plasmodium falciparum, Plasmodium vivax and Plasmodium knowlesi in malaria associated acute kidney injury: a retrospective case …
Objective Acute kidney injury (AKI) is a frequent presentation in malaria infections. Several
cases of AKI that are accompanied by clinical symptoms of malaria infection, such as fever, …
cases of AKI that are accompanied by clinical symptoms of malaria infection, such as fever, …
Characterization of molecular genetic alterations in GBMs highlights a distinctive molecular profile in young adults
To evaluate age-related differences in histopathologic and molecular profile of glioblastomas
(GBMs) at various age groups, with special reference to TP53 mutation, epidermal growth …
(GBMs) at various age groups, with special reference to TP53 mutation, epidermal growth …