Gender‐based effects on methylprednisolone pharmacokinetics and pharmacodynamics
KH Lew, EA Ludwig, MA Milad… - Clinical …, 1993 - Wiley Online Library
The pharmacokinetics and selected pharmacodynamic responses to methylprednisolone
were investigated in six men and six premenopausal women after a dose of 0.6 mg/kg ideal …
were investigated in six men and six premenopausal women after a dose of 0.6 mg/kg ideal …
Lack of pharmacokinetic and pharmacodynamic interactions between ketoconazole and prednisolone
SK Yamashita, EA Ludwig… - Clinical …, 1991 - Wiley Online Library
… To date the pharmacodynamic interaction between ketoconazole and prednisolone (after
administration of oral prednisone) has been studied only by Ludwig et al. ,7 who did not find a …
administration of oral prednisone) has been studied only by Ludwig et al. ,7 who did not find a …
Population pharmacokinetics of tigecycline in patients with complicated intra-abdominal or skin and skin structure infections
SA Van Wart, JS Owen, EA Ludwig… - Antimicrobial agents …, 2006 - Am Soc Microbiol
Tigecycline, a first-in-class expanded glycylcycline antimicrobial agent, has demonstrated
efficacy in the treatment of complicated skin and skin structure infections (cSSSI) and …
efficacy in the treatment of complicated skin and skin structure infections (cSSSI) and …
Pharmacokinetics and pharmacodynamics of methylprednisolone in obesity
TE Dunn, EA Ludwig, RL Slaughter… - Clinical …, 1991 - Wiley Online Library
Methylprednisolone pharmacokinetics and its directly suppressive effects on plasma cortisol,
blood histamine (basophils), and circulating helper T cells were evaluated in six obese (at …
blood histamine (basophils), and circulating helper T cells were evaluated in six obese (at …
Pharmacokinetics and pharmacodynamic modeling of direct suppression effects of methylprednisolone on serum cortisol and blood histamine in human subjects
AN Kong, EA Ludwig, RL Slaughter… - Clinical …, 1989 - Wiley Online Library
… This, plus findings of markedly reduced clearances in patients with cirrhosis (Ludwig EA,
Kong AN, Camara DS, Jusko WJ. July 1989. Unpublished observations) and the small degree …
Kong AN, Camara DS, Jusko WJ. July 1989. Unpublished observations) and the small degree …
Population pharmacokinetics of risperidone and 9-hydroxyrisperidone in patients with acute episodes associated with bipolar I disorder
A Vermeulen, V Piotrovsky, EA Ludwig - Journal of pharmacokinetics and …, 2007 - Springer
A population model was developed with the aim to simultaneously describe risperidone and
9-hydroxyrisperidone pharmacokinetics; to obtain estimates for pharmacokinetic …
9-hydroxyrisperidone pharmacokinetics; to obtain estimates for pharmacokinetic …
Evaluation of dose-related pharmacokinetics and pharmacodynamics of prednisolone in man
JA Wald, RM Law, EA Ludwig, RR Sloan… - … of pharmacokinetics and …, 1992 - Springer
The pharmacokinetics and pharmacodynamics of prednisolone were evaluated in normal
male volunteers. Seven subjects completed 3 phases: 16.4−and 49.2−mg iv prednisolone, …
male volunteers. Seven subjects completed 3 phases: 16.4−and 49.2−mg iv prednisolone, …
Population pharmacokinetic meta-analysis of trabectedin (ET-743, yondelis®) in cancer patients
…, S Hirankam, K Stuyckens, EA Ludwig… - Clinical …, 2007 - Springer
… Ludwig … Laverdiere C, Kolb EA, Supko JG, et al. Phase II study of ecteinascidin 743 in
heavily pretreated patients with recurrent osteosarcoma. Cancer 2003; 98: 832–40 …
heavily pretreated patients with recurrent osteosarcoma. Cancer 2003; 98: 832–40 …
Population pharmacokinetics and pharmacodynamics of garenoxacin in patients with community-acquired respiratory tract infections
S Van Wart, L Phillips, EA Ludwig… - Antimicrobial agents …, 2004 - Am Soc Microbiol
Garenoxacin (T-3811ME, BMS-284756) is a novel, broad-spectrum des-F(6) quinolone
currently under study for the treatment of community-acquired respiratory tract infections. This …
currently under study for the treatment of community-acquired respiratory tract infections. This …
Pharmacokinetics and pharmacodynamics of methylprednisolone when administered at 8 AM versus 4 PM
LE Fisher, EA Ludwig, JA Wald… - Clinical …, 1992 - Wiley Online Library
The temporal variations in the pharmacokinetics and pharmacodynamics of methylprednisolone
at 8 AM versus 4 PM were investigated in six healthy male volunteers. Subjects …
at 8 AM versus 4 PM were investigated in six healthy male volunteers. Subjects …