cDNA cloning of human liver monoamine oxidase A and B: molecular basis of differences in enzymatic properties.
AW Bach, NC Lan, DL Johnson… - Proceedings of the …, 1988 - National Acad Sciences
The monoamine oxidases play a vital role in the metabolism of biogenic amines in the central
nervous system and in peripheral tissues. Using oligonucleotide probes derived from three …
nervous system and in peripheral tissues. Using oligonucleotide probes derived from three …
GRIP1, a novel mouse protein that serves as a transcriptional coactivator in yeast for the hormone binding domains of steroid receptors.
…, K Kohli, A Trivedi, DL Johnson… - Proceedings of the …, 1996 - National Acad Sciences
The yeast two-hybrid system was used to isolate a clone from a 17-day-old mouse embryo
cDNA library that codes for a novel 812-aa long protein fragment, glucocorticoid receptor-…
cDNA library that codes for a novel 812-aa long protein fragment, glucocorticoid receptor-…
Protease inhibitor-associated hyperglycaemia
MP Dubé, DL Johnson, JS Currier, JM Leedom - The Lancet, 1997 - thelancet.com
Inherited mutations in the BRCA1 gene confer a predisposition to breast and ovarian cancer.
1 We report the results of BRCA1-mutation screening in a family at high risk of breast and …
1 We report the results of BRCA1-mutation screening in a family at high risk of breast and …
RNA-dependent replication and transcription of hepatitis delta virus RNA involve distinct cellular RNA polymerases
…, TB Macnaughton, N Zhu, DL Johnson… - … and cellular biology, 2000 - Am Soc Microbiol
Cellular DNA-dependent RNA polymerase II (pol II) has been postulated to carry out RNA-dependent
RNA replication and transcription of hepatitis delta virus (HDV) RNA, generating a …
RNA replication and transcription of hepatitis delta virus (HDV) RNA, generating a …
[HTML][HTML] p53 represses RNA polymerase III transcription by targeting TBP and inhibiting promoter occupancy by TFIIIB
…, LJ Warnock, J Milner, RJ White, DL Johnson - The EMBO …, 2003 - embopress.org
The tumor suppressor p53 is a transcription factor that controls cellular growth and proliferation.
p53 targets include RNA polymerase (pol) III‐dependent genes encoding untranslated …
p53 targets include RNA polymerase (pol) III‐dependent genes encoding untranslated …
[PDF][PDF] Mammalian Maf1 is a negative regulator of transcription by all three nuclear RNA polymerases
SS Johnson, C Zhang, J Fromm, IM Willis, DL Johnson - Molecular cell, 2007 - cell.com
Most eukaryotic transcriptional regulators act in an RNA polymerase (Pol)-selective manner.
Here we show that the human Maf1 protein negatively regulates transcription by all three …
Here we show that the human Maf1 protein negatively regulates transcription by all three …
[HTML][HTML] Enhanced RNA Polymerase III-dependent Transcription Is Required for Oncogenic Transformation*♦
SAS Johnson, L Dubeau, DL Johnson - Journal of Biological Chemistry, 2008 - ASBMB
RNA polymerase (pol) III transcription, responsible for the synthesis of various stable RNAs,
including 5 S rRNAs and tRNAs, is regulated by oncogenic proteins and tumor suppressors. …
including 5 S rRNAs and tRNAs, is regulated by oncogenic proteins and tumor suppressors. …
[HTML][HTML] Maf1 is a novel target of PTEN and PI3K signaling that negatively regulates oncogenesis and lipid metabolism
…, SAS Johnson, L He, N Zheng, L Dubeau… - PLoS …, 2014 - journals.plos.org
Maf1 was initially identified as a transcriptional repressor of RNA pol III-transcribed genes,
yet little is known about its other potential target genes or its biological function. Here, we …
yet little is known about its other potential target genes or its biological function. Here, we …
PTEN represses RNA polymerase III-dependent transcription by targeting the TFIIIB complex
A Woiwode, SAS Johnson, S Zhong… - … and cellular biology, 2008 - Taylor & Francis
PTEN, a tumor suppressor whose function is frequently lost in human cancers, possesses a
lipid phosphatase activity that represses phosphatidylinositol 3-kinase (PI3K) signaling, …
lipid phosphatase activity that represses phosphatidylinositol 3-kinase (PI3K) signaling, …
PTEN represses RNA Polymerase I transcription by disrupting the SL1 complex
C Zhang, L Comai, DL Johnson - Molecular and cellular biology, 2005 - Taylor & Francis
PTEN is a tumor suppressor whose function is frequently lost in human cancer. It possesses
a lipid phosphatase activity that represses the activation of PI3 kinase/Akt signaling, leading …
a lipid phosphatase activity that represses the activation of PI3 kinase/Akt signaling, leading …