Platelet‐derived growth factor stimulates bone fill and rate of attachment level gain: Results of a large multicenter randomized controlled trial

…, PK McClain, ML Nevins, DW Paquette… - Journal of …, 2005 - Wiley Online Library
Background: Growth factors are generally accepted to be essential mediators of tissue repair
via well‐established mechanisms of action that include stimulatory effects on angiogenesis …

Soft tissue reactions to non‐submerged unloaded titanium implants in beagle dogs

…, K Donath, JP Fiorellini, DW Paquette… - Journal of …, 1992 - Wiley Online Library
The soft tissue reactions to non‐submerged unloaded titanium implants were examined. A
total of 24 implants were placed in 6 beagle dogs. The implants differed in their crestal area …

A phase I/II clinical trial to evaluate a combination of recombinant human platelet‐derived growth factor‐BB and recombinant human insulin‐like growth factor‐I in …

TH Howell, JP Fiorellini, DW Paquette… - Journal of …, 1997 - Wiley Online Library
The primary objective of this study was to assess the safety of recombinant human (rh)
platelet‐derived growth factor‐BB (PDGF‐BB) and (rh) insulin‐like growth factor‐I (IGF‐I) when …

Results from the Periodontitis and Vascular Events (PAVE) Study: a pilot multicentered, randomized, controlled trial to study effects of periodontal therapy in a …

…, K Moss, L Mendoza, DW Paquette… - Journal of …, 2009 - Wiley Online Library
Background: In the Periodontitis and Vascular Events (PAVE) pilot study, periodontal therapy
was provided as an intervention in a secondary cardiac event prevention model through …

Treatment of periodontitis by local administration of minocycline microspheres: a controlled trial

RC Williams, DW Paquette… - Journal of …, 2001 - Wiley Online Library
Background: Periodontitis is an inflammatory condition of toothsupporting tissues that is usually
treated by mechanical removal of plaque and microorganisms that adhere to teeth. This …

The effect of nonsurgical periodontal therapy on hemoglobin A1c levels in persons with type 2 diabetes and chronic periodontitis: a randomized clinical trial

…, D Tripathy, JA Katancik, PR Orlander, DW Paquette… - Jama, 2013 - jamanetwork.com
Importance Chronic periodontitis, a destructive inflammatory disorder of the supporting
structures of the teeth, is prevalent in patients with diabetes. Limited evidence suggests that …

Risk factors for endosseous dental implant failure

DW Paquette, N Brodala, RC Williams - Dental Clinics, 2006 - dental.theclinics.com
A recent report published by the American Dental Association Council on Scientific Affairs
recognized the consistently high rate of endosseous dental implant success or survival in …

Modulation of host inflammatory mediators as a treatment strategy for periodontal diseases.

DW Paquette, RC Williams - Periodontology 2000, 2000 - europepmc.org
Studies ranging from preclinical animal models to human clinical trials support the basic
hypothesis that the inhibition of local arachidonic acid metabolites with nonsteroidal anti-…

The periodontal infection-systemic disease link: a review of the truth or myth.

DW Paquette - Journal of the International Academy of …, 2002 - europepmc.org
Paquette DW … Paquette DW | 0000-0002-5555-1390 … Paquette DW, Madianos P,
Offenbacher S, Beck JD, Williams RC …

Cardiovascular disease, inflammation, and periodontal infection.

DW Paquette, N Brodala, TC Nichols - Periodontology 2000, 2007 - search.ebscohost.com
The article offers information about the pathogenesis, risk factors and current interventions
for cardiovascular diseases. It discusses the latest relevant research data from human …