Abstract
Vigabatrin is a relatively new medication used in the treatment of epilepsia. The present report concerns the use of vigabatrin by a 19-year-old woman. The patient manifested marked gingival overgrowth compatible clinically and histologically with the overgrowth induced by phenytoin, cyclosporine and calcium channel blockers. This is the 1st report of vigabatrin-induced gingival overgrowth. Clinicians should be aware of similar lesions in patients using new anticonvulsants.
Publication types
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Case Reports
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Comparative Study
MeSH terms
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Adult
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Anticonvulsants / adverse effects*
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Calcium Channel Blockers / adverse effects
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Cyclosporine / adverse effects
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Epilepsy, Complex Partial / drug therapy
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Female
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Follow-Up Studies
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Gingival Overgrowth / chemically induced*
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Humans
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Immunosuppressive Agents / adverse effects
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Phenytoin / adverse effects
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Vigabatrin
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gamma-Aminobutyric Acid / adverse effects
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gamma-Aminobutyric Acid / analogs & derivatives*
Substances
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Anticonvulsants
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Calcium Channel Blockers
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Immunosuppressive Agents
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gamma-Aminobutyric Acid
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Phenytoin
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Cyclosporine
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Vigabatrin