Failure of thromboxane synthetase inhibition to improve exercise tolerance in patients with stable angina pectoris

Int J Cardiol. 1984 Mar;5(3):382-5. doi: 10.1016/0167-5273(84)90119-0.

Abstract

We report the results of a double-blind study of dazoxiben in which treatment was continued for 3 weeks in patients with angiographically proven coronary artery disease who were receiving no other antiplatelet drugs.

Publication types

  • Comparative Study

MeSH terms

  • Adult
  • Angina Pectoris / drug therapy*
  • Angina Pectoris / physiopathology
  • Blood Pressure / drug effects
  • Double-Blind Method
  • Heart Rate / drug effects
  • Humans
  • Imidazoles / therapeutic use*
  • Male
  • Middle Aged
  • Oxidoreductases / antagonists & inhibitors*
  • Oxygen Consumption / drug effects
  • Physical Exertion / drug effects
  • Thromboxane-A Synthase / antagonists & inhibitors*

Substances

  • Imidazoles
  • dazoxiben
  • Oxidoreductases
  • Thromboxane-A Synthase