Sources of information for this Seminar were: (1) systematic reviews of dental caries (cariology), including the Cochrane Library, Centre for Reviews and Dissemination, University of York (restoration longevity), and the NIH Consensus Development Conference on Diagnosis and Management of Dental Caries Throughout Life; (2) formally constructed and peer reviewed consensus development papers and statements published in the Proceedings from the International Consensus Workshop on Caries
SeminarDental caries
Section snippets
Definition
Dental caries is the localised destruction of susceptible dental hard tissues by acidic by-products from bacterial fermentation of dietary carbohydrates.4, 6 The signs of the carious demineralisation are seen on the hard dental tissues, but the disease process is initiated within the bacterial biofilm (dental plaque) that covers a tooth surface. Moreover, the very early changes in the enamel are not detected with traditional clinical and radiographic methods. Dental caries is a multifactorial
Pathogenesis
Dental caries results from interactions over time between bacteria that produce acid, a substrate that the bacteria can metabolise, and many host factors that include teeth and saliva. Dental caries results from an ecological imbalance in the physiological equilibrium between tooth minerals and oral microbial biofilms.13, 14 Bacteria live on teeth in microcolonies that are encapsulated in an organic matrix of polysaccharides, proteins, and DNA secreted by the cells, which provides protection
Risk factors
A person's risk of caries can vary with time since many risk factors are changeable. Physical and biological risk factors for enamel or root caries include inadequate salivary flow and composition, high numbers of cariogenic bacteria, insufficient fluoride exposure, gingival recession, immunological components, need for special health care, and genetic factors.4, 19, 20, 21, 22, 23 Caries is related to one's lifestyle, and behavioural factors under a person's control are clearly implicated.
Epidemiology
Comparisons of the global frequency and distribution of dental caries are complicated by diagnostic criteria that differ from study to study,4, 7, 32, 33 but a fall in the prevalence and severity of caries in permanent teeth has been seen in many developed countries over recent decades.3, 34, 35, 36, 37, 38, 39 Also, the rate of progression of the disease slows down with increased age.40 The disease is mainly found in specific teeth and tooth types in both primary and permanent teeth.22, 36 The
Diagnosis
International consensus57 recommends that caries diagnosis, (ie, comprehensive assessment of all patient information by a dentist) is differentiated from lesion detection, (use of objective method to detect disease) and lesion assessment (characterising and monitoring of a lesion once detected). Caries diagnosis, whether in the dental office, during a field survey, or as part of a clinical research project, is done by the visual examination of tooth surfaces, perhaps with the use of a dental
Treatment
Over a long period from the turn of the 20th century dentists have thought of tooth restoration as a cure for dental caries. The focus on restoration and retention of teeth was an advance on the previous treatment method of tooth extraction, and became widely used at a time when there was little knowledge of caries prevention, caries formed quickly, and progression rates were high, but there were few dental practitioners.
In clinical practice, caries management by restorative treatment, despite
Prevention
Discussions about improved methods for caries detection, assessment, and diagnosis for effective caries prevention should not be seen as an alternative to public health and health promotion strategies to reduce the burden of disease before a patient arrives at a dental practice with obvious disease. New clinical developments should work in conjunction with such public health approaches.
In dentistry, the promotion of evidence-based care and the production of clinical guidelines to support
Future research directions
Prevention or control of dental caries cannot be achieved by reliance only on current methods and models of dental care. We need to consider the integrated roles of dental, medical, and other health-care providers and assess effective public health interventions and the introduction of oral health promotion activity linked to general health promotion. Most importantly, caregivers of children could play a major part in keeping children free of obvious dental caries.
Initiatives recently announced
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References (85)
The science and practice of caries prevention
J Am Dent Assoc
(2000)- et al.
Dental caries. An infectious and transmissible disease
Pediatr Clin North Am
(2000) Dental caries, oral health, and pediatricians
Curr Probl Pediatr Adolesc Health Care
(2003)Epidemiology of dental caries. A broad review
Dent Clin North Am
(1999)- et al.
Association between children's experience of socioeconomic disadvantage and adult health: a life-course study
Lancet
(2002) - et al.
Minimal intervention dentistry—a review. FDI Commission Project 1–97
Int Dent J
(2000) - et al.
Short-term consumption of probiotic-containing cheese and its effect on dental caries risk factors
Arch Oral Biol
(2002) - et al.
Bacterial replacement therapy: adapting ‘germ warfare’ to infection prevention
Trends Biotechnol
(2003) - et al.
Physicians' roles in preventing dental caries in preschool children: a summary of the evidence for the US Preventive Services Task Force
Am J Prev Med
(2004) Are we ready to move from operative to non-operative/preventive treatment of dental caries in clinical practice?
Caries Res
(2004)
Take two dentists: a tale of root caries
Dent Update
Oral Microbiology
Concepts of dental caries and their consequences for understanding the disease
Community Dent Oral Epidemiol
What constitutes dental caries? Histopathology of carious enamel and dentin related to the action of cariogenic biofilms
J Dent Res
Modern concepts of caries measurement
J Dent Res
The continuum of dental caries—evidence for a dynamic disease process
J Dent Res
Changing paradigms in concepts on dental caries: consequences for oral health care
Caries Res
The biofilm concept: consequences for future prophylaxis of oral diseases?
Crit Rev Oral Biol Med
Biological mechanisms of early childhood caries
Community Dent Oral Epidemiol
Early Childhood Caries (ECC): what's in a name?
Eur J Paediatr Dent
Risk groups: nursing bottle caries/caries in the elderly
Caries Res
Caries management by risk assessment: consensus statement, April 2002
J Calif Dent Assoc
Genetic influences in caries and periodontal diseases
Crit Rev Oral Biol Med
Risk assessment and epidemiology of dental caries: review of the literature
Pediatr Dent
Dental caries experience in older people over time: what can the larger cohort studies tell us?
Br Dent J
Tobacco use and oral disease
J Dent Educ
Sugars and dental caries
Am J Clin Nutr
Bacterial, behavioral and environmental factors associated with early childhood caries
J Clin Pediatr Dent
Does low birthweight increase the risk of caries? A systematic review
J Dent Educ
Acquisition and transmission of mutans streptococci
J Calif Dent Assoc
Caries prediction—state of the art
Community Dent Oral Epidemiol
National Institutes of Health Consensus Development Conference statement, March 26–28, 2001
J Dent Educ
Reactor paper: risk assessment in dental caries
Visual and visuo-tactile detection of dental caries
J Dent Res
“ICDAS”—an international system for caries detection and assessment being developed to facilitate caries epidemiology, research and appropriate clinical management
Community Dent Health
Clinical manifestations and treatment of caries from 1953 to global changes in the 20th century
Caries Res
Changes in dental caries 1953–2003
Caries Res
The impact of recent changes in the epidemiology of dental caries on guidelines for the use of dental sealants
J Public Health Dent
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