Despite years of research directed at understanding the causes of dental caries and the
development of preventive therapeutics for the management of dental caries, the population …

Remineralization is the natural repair process for caries lesions. We have known about
remineralization for at least a hundred years. However, it is only in recent decades that the …

The first ICNARA conference (International Conference on Novel Anticaries and
Remineralizing Agents) was held in Chile in January, 2008, and the proceedings were …

Caries develops when the equilibrium between de-and remineralization is unbalanced
favoring demineralization. De-and remineralization occur depending on the degree of …

More than 60 y have passed since the widespread introduction of fluoride use and 50 y
since the introduction of sealant therapy. Yet, dental caries remains a significant disease …

Dental caries is a multifactorial disease caused by the interaction of dietary sugars, dental
biofilm, and the dental tissue of the host. It results from repeated cycles of demineralization …

This paper briefly reviews the clinical evidence for, and the science behind, the topical
effects of fluoride in the inhibition and reversal of dental caries. Fluoride from topical sources …

The aim of this paper was to distill recommendations from existing evidence and material on
dental caries remineralization/desensitization discussed at the ICNARA meeting within the …

The demineralisation and remineralisation cycle needs to be controlled in order to prevent
the decomposition of dental tissues. The use of fluoridated products, especially the …

A greater understanding of the dental caries process and improved and more diverse
methodologies to assess early demineralization and caries has enabled development of a …