Transcriptional regulation, which integrates chromatin accessibility, transcription factors and
epigenetic modifications, is crucial for establishing and maintaining cell identity. The …

Human amylin is a small fibrillogenic protein that is the major constituent of pancreatic islet
amyloid, which occurs in most subjects with type 2 diabetes. There is evidence that it can …

Periodontal disease (PD) is a common dental disease associated with the interaction between
dysbiotic oral microbiota and host immunity. It is a prevalent disease, resulting in loss of …

A Cry1Ac-resistant strain (Bt-R) of Helicoverpa armigera, with 2971-fold resistance, was
derived by selection with Cry1Ac toxin for 75 generations. We used cDNA-amplified fragment …

Genome-wide association studies (GWAS) of chronic periodontitis (CP) defined by clinical
criteria alone have had modest success to-date. Here, we refine the CP phenotype by …

Rice leaf diseases are a major cause of declining rice production and quality. The early
identification and control of rice leaf diseases is critical for maintaining rice quality and production…

5-Methylcytosine (m 5 C) is a posttranscriptional RNA modification participating in many
critical bioprocesses, but its functions in human cancer remain unclear. Here, by detecting the …

Inflammasomes are a group of multimolecular intracellular complexes assembled around
several innate immune proteins. Recognition of a diverse range of microbial, stress and …

The tumorigenic mechanism for pancreatic ductal adenocarcinoma (PDAC) is not clear,
although chronic inflammation is implicated. Here, we identified an inflammatory cytokine–…

INTRODUCTION: Although human dental pulp stem cells isolated from healthy teeth have
been extensively characterized, it is unknown whether stem cells also exist in clinically …