Air polishing: a review of current literature

SJ Graumann, ML Sensat… - American Dental …, 2013 - jdh.adha.org
Purpose: Routine tooth polishing continues to be an integral part of clinical practice even
though the concept of selective polishing was introduced in the 1980s. This procedure assists …

[HTML][HTML] Shear stress–induced endothelial adrenomedullin signaling regulates vascular tone and blood pressure

…, N Wettschureck, J Graumann… - The Journal of …, 2019 - Am Soc Clin Investig
Hypertension is a primary risk factor for cardiovascular diseases including myocardial infarction
and stroke. Major determinants of blood pressure are vasodilatory factors such as nitric …

Epigenetic scores for the circulating proteome as tools for disease prediction

…, C Gieger, A Peters, M Waldenberger, J Graumann… - Elife, 2022 - elifesciences.org
Protein biomarkers have been identified across many age-related morbidities. However,
characterising epigenetic influences could further inform disease predictions. Here, we …

Small‐molecule‐mediated chemical knock‐down of MuRF1/MuRF2 and attenuation of diaphragm dysfunction in chronic heart failure

…, A Konzer, J Graumann, P Sehr, J Lewis… - Journal of Cachexia …, 2019 - Wiley Online Library
Background Chronic heart failure (CHF) leads to diaphragm myopathy that significantly
impairs quality of life and worsens prognosis. In this study, we aimed to assess the efficacy of a …

Noncanonical HIPPO/MST signaling via BUB3 and FOXO drives pulmonary vascular cell growth and survival

…, D Lin, J Baust, TN Bachman, J Graumann… - Circulation …, 2022 - Am Heart Assoc
… Furthermore, interaction with BUB3 (as identified in this study) as well as interaction with
mTORC 14 and SARAH domain-binding proteins such as RASSF1 73 may regulate the MST …

Remodeling of ER–plasma membrane contact sites but not STIM1 phosphorylation inhibits Ca2+ influx in mitosis

…, R Kulkarni, AM Billing, J Graumann… - Proceedings of the …, 2019 - National Acad Sciences
Store-operated Ca 2+ entry (SOCE), mediated by the endoplasmic reticulum (ER) Ca 2+
sensor stromal interaction molecule 1 (STIM1) and the plasma membrane (PM) channel Orai1, …

[HTML][HTML] Correction: Epigenetic scores for the circulating proteome as tools for disease prediction

…, C Gieger, A Peters, M Waldenberger, J Graumann… - Elife, 2023 - elifesciences.org
In the study, protein EpiScores are generated and Cox proportional hazards (PH) analyses
are run to test associations between each score and 12 incident diseases in Generation …

Epigenetic scores for the circulating proteome replicate protein-disease predictions as tools for biomarker discovery

…, C Gieger, A Peters, M Waldenberger, J Graumann… - bioRxiv, 2020 - biorxiv.org
Polygenic scores capture the genetic predisposition to complex disease and are powerful
tools for risk stratification. However, such diseases are also largely influenced by …

[HTML][HTML] Protein interactions at the higher plant nuclear envelope: evidence for a linker of nucleoskeleton and cytoskeleton complex

…, V Pawar, SJ Smith, K Graumann - Frontiers in Plant Science, 2014 - frontiersin.org
Following the description of SAD1/UNC84 (SUN) domain proteins in higher plants,
evidence has rapidly increased that plants contain a functional linker of nucleoskeleton and …

[HTML][HTML] Loss of the Mia40a oxidoreductase leads to hepato-pancreatic insufficiency in zebrafish

…, S Sugunan, S Guenther, C Kuenne, J Graumann… - PLoS …, 2018 - journals.plos.org
Development and function of tissues and organs are powered by the activity of mitochondria.
In humans, inherited genetic mutations that lead to progressive mitochondrial pathology …