… of complexes carrying a low density lipoprotein receptor (LDL-R) expression construct led
to detectable but transient expression of LDL-R (41). For reasons not well understood, partial …

… Mulligan and Vanderlinde suggested a model to follow in order to cover the interactions of
the medical, behavioral, dental/ oral and psychosocial factors of older adults [10]. All of these …

A retroviral vector system based on the human immunodeficiency virus (HIV) was developed
that, in contrast to a murine leukemia virus-based counterpart, transduced heterologous …

The Sir2 histone deacetylase functions as a chromatin silencer to regulate recombination,
genomic stability, and aging in budding yeast. Seven mammalian Sir2 homologs have been …

… (R. Mulligan, unpublished plasmid) where the gag/p01 region of MuLV had been subcloned
into pSV2 (Mulligan and Berg, 1980). pSV2-gag/pa/ was digested to completion with Xho I …

… Although this may be an indicator of low mitochondrial activity (and hence quiescence), R.…
We thank Craig Jordan and members of the Mulligan Laboratory, particularly M. 8adelain, …

To compare the ability of different cytokines and other molecules to enhance the immunogenicity
of tumor cells, we generated 10 retroviruses encoding potential immunomodulators and …

Telomere dysfunction activates p53-mediated cellular growth arrest, senescence and apoptosis
to drive progressive atrophy and functional decline in high-turnover tissues. The broader …

The development of cell or gene therapies for diseases involving cells that are widely
distributed throughout the body has been severely hampered by the inability to achieve the …

The transcriptional profiles of mouse embryonic, neural, and hematopoietic stem cells were
compared to define a genetic program for stem cells. A total of 216 genes are enriched in all …