Photodynamic therapy for endodontic disinfection

NS Soukos, PSY Chen, JT Morris, K Ruggiero… - Journal of …, 2006 - Elsevier
The aims of this study were to investigate the effects of photodynamic therapy (PDT) on
endodontic pathogens in planktonic phase as well as on Enterococcus faecalis biofilms in …

[PDF][PDF] Photodynamic therapy in the control of oral biofilms

NS Soukos, JM Goodson - Periodontology 2000, 2011 - photomedics.com
Microbial biofilms in the oral cavity are involved in the etiology of various oral conditions,
including caries, periodontal and endodontic diseases, oral malodor, denture stomatitis, …

Targeted antimicrobial photochemotherapy

NS Soukos, LA Ximenez-Fyvie… - Antimicrobial Agents …, 1998 - Am Soc Microbiol
This study explores a new approach for antimicrobial therapy with light activation of targeted
poly-l-lysine (pL)–chlorine6 (c e6 ) conjugates. The goal was to test the hypothesis that …

Photodynamic treatment of endodontic polymicrobial infection in vitro

…, R Kent, AG Doukas, PP Stashenko, NS Soukos - Journal of …, 2008 - Elsevier
We investigated the photodynamic effects of methylene blue on multispecies root canal
biofilms comprising Actinomyces israelii, Fusobacterium nucleatum subspecies nucleatum, …

Nanoparticle-based endodontic antimicrobial photodynamic therapy

…, R Kent, ACR Tanner, MM Amiji, NS Soukos - Journal of …, 2010 - Elsevier
OBJECTIVE: To study the in vitro effects of poly(lactic-co-glycolic acid) (PLGA) nanoparticles
loaded with the photosensitizer methylene blue (MB) and light against Enterococcus …

Photodynamic effects of toluidine blue on human oral keratinocytes and fibroblasts and Streptococcus sanguis evaluated in vitro

NS Soukos, M Wilson, T Burns… - Lasers in Surgery and …, 1996 - Wiley Online Library
Background and Objective Some oral bacteria are susceptible to killing by red light after their
sensitization with toluidine blue O (TBO). The photochemotherapy of periodontal disease in …

Phototargeting oral black-pigmented bacteria

NS Soukos, S Som, AD Abernethy… - Antimicrobial agents …, 2005 - Am Soc Microbiol
We have found that broadband light (380 to 520 nm) rapidly and selectively kills oral black-pigmented
bacteria (BPB) in pure cultures and in dental plaque samples obtained from …

Photodynamic inactivation of Enterococcus faecalis in dental root canals in vitro

…, R Kent, PP Stashenko, NS Soukos - Lasers in Surgery …, 2007 - Wiley Online Library
Background and Objectives We previously reported the use of a flexible fiber optic that uniformly
distributed light in the root canal space for targeting bacteria after their sensitization with …

Endodontic photodynamic therapy ex vivo

…, R Kent, TC Pagonis, PP Stashenko, NS Soukos - Journal of …, 2011 - Elsevier
INTRODUCTION: The objective of this study was to evaluate the antimicrobial effects of
photodynamic therapy (PDT) on infected human teeth ex vivo. METHODS: Fifty-two freshly …

Photodestruction of human dental plaque bacteria: enhancement of the photodynamic effect by photomechanical waves in an oral biofilm model

NS Soukos, SE Mulholland… - Lasers in Surgery …, 2003 - Wiley Online Library
Background and Objectives Periodontal disease results from the accumulation of subgingival
bacterial biofilms on tooth surfaces. There is reduced susceptibility of these biofilms to …