The 2005 National Institutes of Health (NIH) Consensus Conference proposed new criteria
for diagnosing and scoring the severity of chronic graft-versus-host disease (GVHD). The …

Background Dysfunction of regulatory T (Treg) cells has been detected in diverse inflammatory
disorders, including chronic graft-versus-host disease (GVHD). Interleukin-2 is critical for …

The Ancillary Therapy and Supportive Care Working Group had 3 goals: (1) to establish
guidelines for ancillary therapy and supportive care in chronic graft-versus-host disease (GVHD)…

Oral mucositis (OM) has emerged as a common cause of dose delays and interruptions of
cancer therapies such as multicycle chemotherapy, myeloablative chemotherapy, and …

Background Objective was to determine whether prophylactic low level laser therapy (LLLT)
reduces the risk of severe mucositis as compared to placebo or no therapy. Methods …

The oral cavity sits at the opening of the digestive tract, bounded by the lips anteriorly and
the oropharynx posteriorly, and is supported structurally by the maxillary (upper jaw) and …

Anti-cancer agents that inhibit the mTOR pathway are associated with a number of unique
toxicities, with one of the most significant and potentially dose-limiting being stomatitis. The …

BACKGROUND AND OBJECTIVE: Bisphosphonate-associated osteonecrosis of the jaws (BONJ)
is characterized by exposed nonvital maxillary or mandibular bone. Cone-beam …

purpose. In prior work, it has been found that the meibomian gland is an androgen target
organ, that androgens modulate lipid production within this tissue, and that androgen …

Background Osteoradionecrosis of the jaw (ORN) is an infrequent yet potentially devastating
complication of radiation therapy to the head and neck region. Treatment options include …