Purpose: The demand for esthetic dentistry has led to the development of new treatments
for white spot lesions (WSLs). Microinvasive therapies, such as resin infiltration, have been …

… Results of this study showed that 78% (n=14) of the fluorosed lesions treated with resin
infiltration using TEGDMA demonstrated a significant improvement (p<0.001) indicating …

… (n=28 and 32) and one Neuroendocrine carcinoma (n=27). There is no immediate link
between mechanism of action of the agents in the combinations, and the two Merkel cell …

Background: Patient-derived xenografts (PDXs) are a powerful tool for cancer translational
research. However, it is unclear if early passage PDXs faithfully recapitulate the molecular …

… were corrected for synthesis variability using β-actin as described under Materials and
methods (n=3). … P<0.05 vs vector control, #P<0.05 vs same treatment but no catalase (n=3). …

… study with 39 PDX models of rare cancers (mesothelioma, MPNST, osteosarcoma, Merkel
cell carcinoma, etc) treated with 56 novel therapeutic combinations in an exploratory, n-of-4 …

This project has been funded in whole or in part with Federal funds from the National Cancer
Institute, National Institutes of Health, under Contract No. HHSN261200800001E. The …

Methods High tumor purity in the PDX specimens (after removal of mouse reads representing
the stroma) enabled highly accurate assessment of LoH. As a first step in the identification …

… predicts concentrations at time t n + 1 by accounting for both the current (at t n ) and future (
t … error between the old ( n - 1 ) and updated ( n ) values was met. Newton’s method typically …

… Oxford and Basingstoke samples were selected if the consensus sequence (inferred from
unique mapped reads) consisted of no more than 25% N characters. As an alignment to the …