User profiles for M. A. Ghannoum
Mahmoud GhannoumCase Western Reserve University Verified email at case.edu Cited by 45355 |
Antifungal agents: mode of action, mechanisms of resistance, and correlation of these mechanisms with bacterial resistance
MA Ghannoum, LB Rice - Clinical microbiology reviews, 1999 - Am Soc Microbiol
The increased use of antibacterial and antifungal agents in recent years has resulted in the
development of resistance to these drugs. The significant clinical implication of resistance …
development of resistance to these drugs. The significant clinical implication of resistance …
Development of interpretive breakpoints for antifungal susceptibility testing: conceptual framework and analysis of in vitro-in vivo correlation data for fluconazole …
…, A Espinel-Ingroff, MA Ghannoum… - Clinical Infectious …, 1997 - academic.oup.com
The availability of reproducible antifungal susceptibility testing methods now permits analysis
of data correlating susceptibility in vitro with outcome in vivo in order to define interpretive …
of data correlating susceptibility in vitro with outcome in vivo in order to define interpretive …
Potential role of phospholipases in virulence and fungal pathogenesis
MA Ghannoum - Clinical microbiology reviews, 2000 - Am Soc Microbiol
Microbial pathogens use a number of genetic strategies to invade the host and cause infection.
These common themes are found throughout microbial systems. Secretion of enzymes, …
These common themes are found throughout microbial systems. Secretion of enzymes, …
Biofilm Formation by the Fungal PathogenCandida albicans: Development, Architecture, and Drug Resistance
…, LL Hoyer, T McCormick, MA Ghannoum - Journal of …, 2001 - Am Soc Microbiol
Biofilms are a protected niche for microorganisms, where they are safe from antibiotic
treatment and can create a source of persistent infection. Using two clinically relevant Candida …
treatment and can create a source of persistent infection. Using two clinically relevant Candida …
[HTML][HTML] Characterization of the oral fungal microbiome (mycobiome) in healthy individuals
MA Ghannoum, RJ Jurevic, PK Mukherjee, F Cui… - PLoS …, 2010 - journals.plos.org
The oral microbiome–organisms residing in the oral cavity and their collective genome–are
critical components of health and disease. The fungal component of the oral microbiota has …
critical components of health and disease. The fungal component of the oral microbiota has …
Antifungal Susceptibility of Candida Biofilms: Unique Efficacy of Amphotericin B Lipid Formulations and Echinocandins
…, PK Mukherjee, MA Ghannoum - Antimicrobial agents …, 2002 - Am Soc Microbiol
Biofilms, likely the predominant mode of device-related microbial infection, exhibit resistance
to antimicrobial agents. Evidence suggests that Candida biofilms have dramatically …
to antimicrobial agents. Evidence suggests that Candida biofilms have dramatically …
Antifungal resistance of candidal biofilms formed on denture acrylic in vitro
…, LL Hoyer, LJ Douglas, MA Ghannoum - Journal of dental …, 2001 - journals.sagepub.com
Denture biofilms represent a protective reservoir for oral microbes. The study of the biology
of Candida in these biofilms requires a reliable model. A reproducible model of C. albicans …
of Candida in these biofilms requires a reliable model. A reproducible model of C. albicans …
Antifungal susceptibility testing: practical aspects and current challenges
…, A Espinel-Ingroff, MA Ghannoum… - Clinical microbiology …, 2001 - Am Soc Microbiol
Development of standardized antifungal susceptibility testing methods has been the focus of
intensive research for the last 15 years. Reference methods for yeasts (NCCLS M27-A) and …
intensive research for the last 15 years. Reference methods for yeasts (NCCLS M27-A) and …
A large-scale North American study of fungal isolates from nails: the frequency of onychomycosis, fungal distribution, and antifungal susceptibility patterns
MA Ghannoum, RA Hajjeh, R Scher, N Konnikov… - Journal of the American …, 2000 - Elsevier
Background: Onychomycosis, a fungal infection of the nail bed, is responsible for up to 50%
of nail disorders. Although several surveys have been conducted in different parts of the …
of nail disorders. Although several surveys have been conducted in different parts of the …
Comparison of Biofilms Formed by Candidaalbicans and Candidaparapsilosis on Bioprosthetic Surfaces
…, J Chandra, PK Mukherjee, MA Ghannoum - Infection and …, 2002 - Am Soc Microbiol
Little is known about fungal biofilms, which may cause infection and antibiotic resistance. In
this study, biofilm formation by different Candida species, particularly Candidaalbicans and C…
this study, biofilm formation by different Candida species, particularly Candidaalbicans and C…