Objective Provide recommendations to the cystic fibrosis (CF) community to facilitate timely
referral for lung transplantation for individuals with CF. Methods The CF Foundation …

Background Lung transplantation (LTx) is frequently considered for patients with cystic
fibrosis (CF) when the FEV 1 reaches < 30%. This study estimated transplant-free survival for …

Background Reduced BMI is an absolute contraindication for lung transplantation (LTx) at
most centers in the United States. The objective of this study was to quantify post-LTx survival …

Background Lung transplantation is an intervention that improves survival for adult patients
with cystic fibrosis (CF). Some patients with CF are never referred for lung transplant …

Tens of thousands of patients with advanced lung diseases may be eligible to be considered
as potential candidates for lung transplant around the world each year. The timing of referral…

Background Cystic fibrosis (CF) lung transplant (LT) recipients may warrant treatment with
elexacaftor/tezacaftor/ivacaftor (ETI) to improve extrapulmonary manifestations of CF. Our …

Background Chronic Pseudomonas aeruginosa lung infection is associated with significant
morbidity and mortality in cystic fibrosis (CF). It is not known whether recent advances in care …

Background Little is known about risk factors for chronic and mucoid Pseudomonas aeruginosa
(Pa) infection in cystic fibrosis (CF) adults, and whether the prevalence is changing. …

BACKGROUND Previous literature in cystic fibrosis (CF) has shown a 10-year survival gap
between Canada and the United States (US). We hypothesized that differential access to and …

The last decade has seen development of oral, small molecule therapies that address the
basic cystic fibrosis transmembrane conductance regulator (CFTR) protein defect. Highly …