Major salivary gland function in patients with radiation-induced xerostomia: flow rates and sialochemistry

IH Valdez, JC Atkinson, JA Ship, PC Fox - International Journal of …, 1993 - Elsevier
Radiation therapy for cancer of the head and neck region often causes salivary gland
dysfunction and xerostomia. Several reports suggest that the submandibular/sublingual (SM/SL) …

Salivary hypofunction and xerostomia: diagnosis and treatment

JC Atkinson, M Grisius, W Massey - Dental Clinics, 2005 - dental.theclinics.com
Saliva plays a central role in the maintenance of oral homeostasis. The complex mixture of
proteins, glycoproteins, mucins, and ions helps prevent dental caries, promotes …

Salivary gland dysfunction: causes, symptoms, treatment

JC Atkinson, AJ Wu - The Journal of the American Dental Association, 1994 - Elsevier
Conditions that cause reduced salivary output as well as treatment options are discussed.
The three most common known causes of salivary gland dysfunction are medication usage, …

Pilocarpine treatment of salivary gland hypofunction and dry mouth (xerostomia)

PC Fox, JC Atkinson, AA Macynski… - Archives of Internal …, 1991 - jamanetwork.com
We studied the effects of pilocarpine hydrochloride, a parasympathomimetic agent, on major
salivary gland output and subjective responses in 31 patients with salivary hypofunction. …

Management of oral lesions in HIV-positive patients

L Baccaglini, JC Atkinson, LL Patton, M Glick… - Oral Surgery, Oral …, 2007 - Elsevier
HIV/AIDS is currently the leading cause of death in Africa and the fourth leading cause of
death worldwide. This systematic review of the literature was conducted to evaluate the …

Stability of bisphenol A, triethylene-glycol dimethacrylate, and bisphenol A dimethacrylate in whole saliva

JC Atkinson, F Diamond, F Eichmiller, R Selwitz… - Dental Materials, 2002 - Elsevier
Objectives: This study investigated the stability of compounds of dental sealant materials in
a salivary matrix. Methods: Various amounts of bisphenol A (BPA), bisphenol A …

Randomized, double-blind, placebo-controlled phase IIb trial of the cyclooxygenase inhibitor ketorolac as an oral rinse in oropharyngeal leukoplakia

JL Mulshine, JC Atkinson, RO Greer… - Clinical cancer …, 2004 - AACR
Purpose: Nonselective cyclooxygenase (COX) inhibitors have been reported to decrease
the frequency of upper aerodigestive cancers. Ketorolac tromethamine oral rinse has been …

Salivary gland dysfunction

JC Atkinson, PC Fox - Clinics in geriatric medicine, 1992 - Elsevier
A clinically significant decline in salivary output in a geriatric patient is not a consequence of
aging. It is more likely that the patient is taking a medication that inhibits salivation, or he or …

[HTML][HTML] Salivary gland involvement in chronic graft-versus-host disease: prevalence, clinical significance, and recommendations for evaluation

MM Imanguli, JC Atkinson, SA Mitchell, DN Avila… - Biology of Blood and …, 2010 - Elsevier
Although xerostomia is a commonly reported complaint in patients with chronic graft-versus-host
disease (cGVHD), criteria for evaluating the prevalence and characteristics of salivary …

Use of pilocarpine during head and neck radiation therapy to reduce xerostomia and salivary dysfunction

IH Valdez, A Wolff, JC Atkinson, AA Macynski, PC Fox - Cancer, 1993 - Wiley Online Library
Background. Salivary gland hypofunction commonly develops during radiation therapy to
the head and neck region. This study evaluated whether the sialogogue pilocarpine given …