User profiles for J. A. Janssen
Joseph AMJL JanssenAssociate Professor, Internal Medicine, Erasmus MC, Rotterdam Verified email at erasmusmc.nl Cited by 11905 |
Study of the molecular mechanism of decreased liver synthesis of albumin in inflammation.
HJ Moshage, JA Janssen, JH Franssen… - The Journal of …, 1987 - Am Soc Clin Investig
Hypoalbuminemia in inflammatory disorders is not an infrequent finding. However, little is
known about albumin synthesis in these patients. In the present study we have measured the …
known about albumin synthesis in these patients. In the present study we have measured the …
High bone mineral density and fracture risk in type 2 diabetes as skeletal complications of inadequate glucose control: the Rotterdam Study
…, L Stolk, EHG Oei, JBJ van Meurs, JA Janssen… - Diabetes …, 2013 - Am Diabetes Assoc
OBJECTIVE Individuals with type 2 diabetes have increased fracture risk despite higher
bone mineral density (BMD). Our aim was to examine the influence of glucose control on …
bone mineral density (BMD). Our aim was to examine the influence of glucose control on …
Identification of the BclI polymorphism in the glucocorticoid receptor gene: association with sensitivity to glucocorticoids in vivo and body mass index
…, P Arp, W Ester, JA Janssen… - Clinical …, 2003 - Wiley Online Library
objective Sensitivity to glucocorticoids differs between individuals, partially due to genetic
variation in the glucocorticoid receptor (GR) gene. We studied the sequence alteration of a …
variation in the glucocorticoid receptor (GR) gene. We studied the sequence alteration of a …
Insulin-like growth factors, their binding proteins, and prostate cancer risk: analysis of individual patient data from 12 prospective studies
Background: Some, but not all, published results have shown an association between
circulating blood levels of some insulin-like growth factors (IGFs) and their binding proteins (…
circulating blood levels of some insulin-like growth factors (IGFs) and their binding proteins (…
A polymorphism in the glucocorticoid receptor gene, which decreases sensitivity to glucocorticoids in vivo, is associated with low insulin and cholesterol levels
…, NATM Huizenga, AG Uitterlinden, JA Janssen… - Diabetes, 2002 - Am Diabetes Assoc
We investigated whether a polymorphism in codons 22 and 23 of the glucocorticoid (GC)
receptor gene [GAGAGG(GluArg) → GAAAAG(GluLys)] is associated with altered GC sensitivity…
receptor gene [GAGAGG(GluArg) → GAAAAG(GluLys)] is associated with altered GC sensitivity…
A polymorphism in the gene for IGF-I: functional properties and risk for type 2 diabetes and myocardial infarction
N Vaessen, P Heutink, JA Janssen, JCM Witteman… - Diabetes, 2001 - Am Diabetes Assoc
Evidence is accumulating that low levels of IGF-I play a role in the pathogenesis of type 2
diabetes and cardiovascular diseases. We examined the role of a genetic polymorphism in the …
diabetes and cardiovascular diseases. We examined the role of a genetic polymorphism in the …
Ghrelin stimulates, whereas des-octanoyl ghrelin inhibits, glucose output by primary hepatocytes
…, PJD Delhanty, LJ Hofland, JA Janssen… - The Journal of …, 2005 - academic.oup.com
Ghrelin exerts various metabolic activities, including regulation of glucose levels in humans.
To verify whether the glucose response to ghrelin reflects a modulation of an insulin-…
To verify whether the glucose response to ghrelin reflects a modulation of an insulin-…
[HTML][HTML] Hyperinsulinemia and its pivotal role in aging, obesity, type 2 diabetes, cardiovascular disease and cancer
JA Janssen - International journal of molecular sciences, 2021 - mdpi.com
For many years, the dogma has been that insulin resistance precedes the development of
hyperinsulinemia. However, recent data suggest a reverse order and place hyperinsulinemia …
hyperinsulinemia. However, recent data suggest a reverse order and place hyperinsulinemia …
The effect of host size on quality attributes of the egg parasitoid, Trichogramma pretiosum
…, L Forster, B Stephens, JAM Janssen - Entomologia …, 1992 - Wiley Online Library
In a study of the quality of Trichogramma pretiosum Riley (Hymenoptera: Trichogrammidae),
we compared female wasps emerging from natural hosts, parasitized in the laboratory or …
we compared female wasps emerging from natural hosts, parasitized in the laboratory or …
Association between genetic variation in the gene for insulin-like growth factor-l and low birthweight
N Vaessen, JA Janssen, P Heutink, A Hofman… - The Lancet, 2002 - thelancet.com
Low birthweight is associated with later risk of type 2 diabetes and related disorders. We aimed
to show that a polymorphism in the gene for insulin-like growth factor-l, which has proved …
to show that a polymorphism in the gene for insulin-like growth factor-l, which has proved …