Tamoxifen significantly reduces tumor recurrence in certain patients with early-stage estrogen
receptor-positive breast cancer, but markers predictive of treatment failure have not been …

Bacterial communities in the airways of cystic fibrosis (CF) patients are, as in other ecological
niches, influenced by autogenic and allogenic factors. However, our understanding of …

Heart failure is one of the leading causes of death worldwide and has been singled out as
an emerging epidemic. 1, 2 With a 5-year survival rate of 50%, heart failure poses a …

Background Patients often require a rapid sequence induction (RSI) endotracheal intubation
technique during emergencies or electively to protect against aspiration, increased …

The increasing availability of electronic health records (EHRs) creates opportunities for
automated extraction of information from clinical text. We hypothesized that natural language …

Objectives. We examined whether perceived unfair treatment is associated with health
conditions, whether social support moderates this association, and whether such relationships …

Nicotinamide adenine dinucleotide phosphate (NADP + ) is vital to produce NADPH, a
principal supplier of reducing power for biosynthesis of macromolecules and protection against …

Photochemical internalisation (PCI) is a novel technology for release of endocytosed
macromolecules into the cytosol. The technology is based on the use of photosensitizers that locate …

Importance Excessive bleeding is a common complication of cardiac surgery. An important
cause of bleeding is acquired hypofibrinogenemia (fibrinogen level <1.5-2.0 g/L), for which …

Purine nucleotides are necessary for various biological processes related to cell proliferation.
Despite their importance in DNA and RNA synthesis, cellular signaling, and energy-…