Neurotransmitter-related enzymes and indices of hypoxia in senile dementia and other abiotrophies.
DM Bowen, CB Smith, P White… - Brain: a journal of …, 1976 - europepmc.org
Fifty-six brains from middle-aged and elderly normal as well as demented subjects and
patients with provisional clinical diagnosis of other neurological and psychiatric diseases were …
patients with provisional clinical diagnosis of other neurological and psychiatric diseases were …
Alzheimer's disease: correlation of cortical choline acetyltransferase activity with the severity of dementia and histological abnormalities
GK Wilcock, MM Esiri, DM Bowen, CCT Smith - Journal of the neurological …, 1982 - Elsevier
We have examined the choline acetyltransferase [CAT] activity in autopsy samples of frontal
and temporal lobe cortex from 47 patients (31 with Alzheimer's disease, 4 with dementia due …
and temporal lobe cortex from 47 patients (31 with Alzheimer's disease, 4 with dementia due …
Presynaptic cholinergic dysfunction in patients with dementia
NR Sims, DM Bowen, SJ Allen… - Journal of …, 1983 - Wiley Online Library
Indices of presynaptic cholinergic nerve endings were assayed in neocortical biopsy samples
from patients with presenile dementia. For those patients in whom Alzheimer's disease …
from patients with presenile dementia. For those patients in whom Alzheimer's disease …
Biochemical assessment of serotonergic and cholinergic dysfunction and cerebral atrophy in Alzheimer's disease
DM Bowen, SJ Allen, JS Benton… - Journal of …, 1983 - Wiley Online Library
Markers of serotonin synapses in entire temporal lobe and frontal and temporal neocortex
were examined for changes in Alzheimer's disease by use of both neurosurgical and autopsy …
were examined for changes in Alzheimer's disease by use of both neurosurgical and autopsy …
Polymersome carriers: from self-assembly to siRNA and protein therapeutics
DA Christian, S Cai, DM Bowen, Y Kim… - European Journal of …, 2009 - Elsevier
Polymersomes are polymer-based vesicular shells that form upon hydration of amphiphilic
block copolymers. These high molecular weight amphiphiles impart physicochemical …
block copolymers. These high molecular weight amphiphiles impart physicochemical …
Neocortical cholinergic neurons in elderly people
…, CR Hiley, LH Carrasco, IEI Williams, DM Bowen - The Lancet, 1977 - Elsevier
… Retrospective analysis of our tumour records has revealed another patient with a pancreatic
D-cell tumour and achlorhydria, steatorrhoea, and diabetes mellitus. The symptoms may be …
D-cell tumour and achlorhydria, steatorrhoea, and diabetes mellitus. The symptoms may be …
Neurochemical studies of early-onset Alzheimer's disease: possible influence on treatment
Multiple neurotransmitter deficits found in recent autopsy studies of patients with Alzheimer's
disease may militate against the success of "simple cholinergic replacement" as treatment. …
disease may militate against the success of "simple cholinergic replacement" as treatment. …
Monoaminergic innervation of the frontal and temporal lobes in Alzheimer's disease
…, GK Wilcock, MM Esiri, PT Francis, DM Bowen - Brain research, 1987 - Elsevier
… and Bowen, DM, Binding of the novel serotonin agonist 8-hydroxy-2(di-n-propylamino) tetralin
in normal … 31 Palmer, AM, Francis, PT and Bowen, DM, Stability of noradrenaline and 5-…
in normal … 31 Palmer, AM, Francis, PT and Bowen, DM, Stability of noradrenaline and 5-…
Presynaptic serotonergic dysfunction in patients with Alzheimer's disease
…, D Neary, JS Snowden, DM Bowen - Journal of …, 1987 - Wiley Online Library
Indices of presynaptic serotonergic nerve endings were assayed in neocortical biopsy
samples from patients with histologically verified Alzheimer's disease. The concentrations of 5‐…
samples from patients with histologically verified Alzheimer's disease. The concentrations of 5‐…
Alzheimer's disease: a correlative study.
…, JS Snowden, DM Mann, DM Bowen… - Journal of Neurology …, 1986 - jnnp.bmj.com
In a study of 17 patients with histologically proven Alzheimer's disease the relationship between
psychological, pathological and chemical measures of disorder was examined. Severity …
psychological, pathological and chemical measures of disorder was examined. Severity …