Effective fiber hypertrophy in satellite cell-depleted skeletal muscle
…, EE Dupont-Versteegden, CA Peterson - …, 2011 - journals.biologists.com
An important unresolved question in skeletal muscle plasticity is whether satellite cells are
necessary for muscle fiber hypertrophy. To address this issue, a novel mouse strain (Pax7-…
necessary for muscle fiber hypertrophy. To address this issue, a novel mouse strain (Pax7-…
Inducible depletion of satellite cells in adult, sedentary mice impairs muscle regenerative capacity without affecting sarcopenia
…, EE Dupont-Versteegden, JJ McCarthy, CA Peterson - Nature medicine, 2015 - nature.com
A key determinant of geriatric frailty is sarcopenia, the age-associated loss of skeletal muscle
mass and strength 1 , 2 . Although the etiology of sarcopenia is unknown, the correlation …
mass and strength 1 , 2 . Although the etiology of sarcopenia is unknown, the correlation …
[PDF][PDF] Myogenic progenitor cells control extracellular matrix production by fibroblasts during skeletal muscle hypertrophy
Satellite cells, the predominant stem cell population in adult skeletal muscle, are activated
in response to hypertrophic stimuli and give rise to myogenic progenitor cells (MPCs) within …
in response to hypertrophic stimuli and give rise to myogenic progenitor cells (MPCs) within …
Satellite cell depletion does not inhibit adult skeletal muscle regrowth following unloading-induced atrophy
…, JJ McCarthy, CA Peterson… - … of Physiology-Cell …, 2012 - journals.physiology.org
Resident muscle stem cells, known as satellite cells, are thought to be the main mediators of
skeletal muscle plasticity. Satellite cells are activated, replicate, and fuse into existing …
skeletal muscle plasticity. Satellite cells are activated, replicate, and fuse into existing …
[HTML][HTML] Differential requirement for satellite cells during overload-induced muscle hypertrophy in growing versus mature mice
…, EE Dupont-Versteegden, JJ McCarthy, CA Peterson - Skeletal muscle, 2017 - Springer
Background Pax7+ satellite cells are required for skeletal muscle fiber growth during post-natal
development in mice. Satellite cell-mediated myonuclear accretion also appears to …
development in mice. Satellite cell-mediated myonuclear accretion also appears to …
[HTML][HTML] Regulation of the muscle fiber microenvironment by activated satellite cells during hypertrophy
…, JJ McCarthy, CA Peterson - The FASEB …, 2014 - ncbi.nlm.nih.gov
Our aim in the current study was to determine the necessity of satellite cells for long-term
muscle growth and maintenance. We utilized a transgenic Pax7-DTA mouse model, allowing …
muscle growth and maintenance. We utilized a transgenic Pax7-DTA mouse model, allowing …
[HTML][HTML] Inducible Cre transgenic mouse strain for skeletal muscle-specific gene targeting
Background The use of the Cre/loxP system for gene targeting has been proven to be a
powerful tool for understanding gene function. The purpose of this study was to create and …
powerful tool for understanding gene function. The purpose of this study was to create and …
Selective accumulation of MyoD and myogenin mRNAs in fast and slow adult skeletal muscle is controlled by innervation and hormones
…, CM Gurley, WJ Carter, CA Peterson - …, 1993 - journals.biologists.com
Each of the myogenic helix-loop-helix transcription factors (MyoD, Myogenin, Myf-5, and
MRF4) is capable of activating muscle-specific gene expression, yet distinct functions have not …
MRF4) is capable of activating muscle-specific gene expression, yet distinct functions have not …
Adipose tissue macrophages in insulin-resistant subjects are associated with collagen VI and fibrosis and demonstrate alternative activation
…, CM Gurley, B Zhu, CA Peterson… - American Journal …, 2010 - journals.physiology.org
Adipose tissue macrophages are associated with insulin resistance and are linked to changes
in the extracellular matrix. To better characterize adipose macrophages, the extracellular …
in the extracellular matrix. To better characterize adipose macrophages, the extracellular …
Expression of CD68 and macrophage chemoattractant protein-1 genes in human adipose and muscle tissues: association with cytokine expression, insulin resistance …
…, T Lu, LM Miles, G Ranganathan, CA Peterson… - Diabetes, 2005 - Am Diabetes Assoc
To examine the role of adipose-resident macrophages in insulin resistance, we examined the
gene expression of CD68, a macrophage marker, along with macrophage chemoattractant …
gene expression of CD68, a macrophage marker, along with macrophage chemoattractant …