Chronology of mitochondrial and cellular events during skeletal muscle ischemia-reperfusion

S Paradis, AL Charles, A Meyer… - … of Physiology-Cell …, 2016 - journals.physiology.org
Peripheral artery disease (PAD) is a common circulatory disorder of the lower limb arteries
that reduces functional capacity and quality of life of patients. Despite relatively effective …

[HTML][HTML] Mitochondria: an organelle of bacterial origin controlling inflammation

A Meyer, G Laverny, L Bernardi, AL Charles… - Frontiers in …, 2018 - frontiersin.org
Inflammation is a cellular and molecular response to infection and/or tissues injury. While a
suited inflammatory response in intensity and time allows for killing pathogens, clearing …

Skeletal muscle mitochondrial dysfunction during chronic obstructive pulmonary disease: central actor and therapeutic target

A Meyer, J Zoll, AL Charles, A Charloux… - Experimental …, 2013 - Wiley Online Library
Anne Laure CharlesAnne Laure Charles … We gratefully thank Anne-Marie Kasprowicz
for expert secretarial assistance and Pierre Pothier for careful language reviewing of the …

Opposite effects of statins on mitochondria of cardiac and skeletal muscles: a 'mitohormesis' mechanism involving reactive oxygen species and PGC-1

J Bouitbir, AL Charles, A Echaniz-Laguna… - European heart …, 2012 - academic.oup.com
Aims Statins protect against cardiovascular-related mortality but induce skeletal muscle
toxicity. To investigate mechanisms of statins, we tested the hypothesis that statins optimized …

Enhanced-reality video fluorescence: a real-time assessment of intestinal viability

…, B Barry, IJ Namer, N Demartines, AL Charles… - Annals of …, 2014 - journals.lww.com
Objective: Our aim was to evaluate a fluorescence-based enhanced-reality system to assess
intestinal viability in a laparoscopic mesenteric ischemia model. Materials and Methods: A …

[HTML][HTML] Tetrahydrocannabinol induces brain mitochondrial respiratory chain dysfunction and increases oxidative stress: a potential mechanism involved in cannabis …

…, AI Schlagowski, O Rouyer, AL Charles… - BioMed research …, 2015 - hindawi.com
Cannabis has potential therapeutic use but tetrahydrocannabinol (THC), its main psychoactive
component, appears as a risk factor for ischemic stroke in young adults. We therefore …

[HTML][HTML] Reductive stress impairs myoblasts mitochondrial function and triggers mitochondrial hormesis

F Singh, AL Charles, AI Schlagowski, J Bouitbir… - … et Biophysica Acta (BBA …, 2015 - Elsevier
Even though oxidative stress damage from excessive production of ROS is a well known
phenomenon, the impact of reductive stress remains poorly understood. This study tested the …

IFN-β-induced reactive oxygen species and mitochondrial damage contribute to muscle impairment and inflammation maintenance in dermatomyositis

…, B Lannes, G Alsaleh, AL Charles… - Acta …, 2017 - Springer
Dermatomyositis (DM) is an autoimmune disease associated with enhanced type I interferon
(IFN) signalling in skeletal muscle, but the mechanisms underlying muscle dysfunction and …

Sarcopenia and peripheral arterial disease: a systematic review

M Pizzimenti, A Meyer, AL Charles… - Journal of cachexia …, 2020 - Wiley Online Library
Background Patients with lower extremity peripheral arterial disease (PAD) and sarcopenia
are a population at risk requiring specific and targeted care. The aim of this review is to …

Mitochondria: mitochondrial participation in ischemia–reperfusion injury in skeletal muscle

A Lejay, A Meyer, AI Schlagowski, AL Charles… - The international journal …, 2014 - Elsevier
Irrespective of the organ involved, restoration of blood flow to ischemic tissue is vital, although
reperfusion per se is deleterious. In the setting of vascular surgery, even subtle skeletal …