Virus-induced interlukin-1β (IL-1β) and IL-18 production in macrophages are mediated via
caspase-1 pathway. Multiple microbial components, including viral RNA, are thought to …

Background: Advance care planning (ACP) documents patient wishes and increases
awareness of palliative care options. Objective: To study the association of outpatient ACP with …

Abstract: This systematic review assessed peer-reviewed research studies on mortality rates
of the homeless population within the United States. Extrapolated data included definitions …

The outcome for metastatic pediatric osteosarcoma (OS) remains poor. Thus, there is an urgent
need to develop novel therapies, and immunotherapy with CAR T cells has the potential …

Osteonecrosis is a common dose-limiting toxicity of glucocorticoids. Data from clinical trials
suggest that other medications can increase the risk of glucocorticoid-induced osteonecrosis. …

Patients undergoing glucocorticoid therapy for a variety of disorders, including autoimmune
diseases and hematological malignancies, are at risk of developing osteonecrosis. Despite …

Sibling grief is linked to serious physical and mental health outcomes, yet remains the least
researched of all family bereavement. This exploratory study created a shared sibling grief …

Lead discovery in osteosarcoma has been hampered by the lack of new agents, limited
representative clinical samples and paucity of accurate preclinical models. We developed …

The NOD.Cg-Prkdc scid Il2rg tm1Wjl /SzJ strain (NOD scid gamma, NSG) is a severely
immunodeficient inbred laboratory mouse used for preclinical studies because it is amenable to …

Photoaffinity labeling is a useful technique employed to identify protein–ligand and protein–protein
noncovalent interactions. Photolabeling experiments have been particularly …