Glioblastoma is the most common primary malignant brain tumor in adults and is associated
with poor survival. The Ivy Foundation Early Phase Clinical Trials Consortium conducted a …

Through litter decomposition enormous amounts of carbon is emitted to the atmosphere.
Numerous large-scale decomposition experiments have been conducted focusing on this …

Recognition of the multiple roles of Hedgehog signaling in cancer has prompted intensive
efforts to develop targeted pathway inhibitors. Leading inhibitors in clinical development act …

MIF is a proinflammatory cytokine and is implicated in cancer. A higher MIF level is found in
many human cancer and cancer‐prone inflammatory diseases, including chronic …

Purpose: To identify metabolic pathways that are perturbed in pancreatic ductal adenocarcinoma
(PDAC), we investigated gene-metabolite networks with integration of metabolomics …

Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal cancers worldwide. To
identify biologically relevant genes with prognostic and therapeutic significance in PDAC, we …

To the Editor—Rapid advances in DNA-sequencing and bioinformatics technologies in the
past two decades have substantially improved understanding of the microbial world. This …

Rheumatoid arthritis (RA) is the most common systemic autoimmune disease, affecting ∼1%
of the adult population worldwide, with an estimated heritability of 60%. To identify genes …

We present QIIME 2, an opensource microbiome data science platform accessible to users
spanning the microbiome research ecosystem, from scientists and engineers to clinicians …

We have demonstrated previously the oncolytic effects of a systemically delivered, replicating
vaccinia virus. To enhance the tumor specificity of this vector, we have developed a …