@article {Charles40, author = {Christine A Charles and Toni Anne Lisante and Ratna Revankar and Jose Roberto Cortelli and Sheila Cavalca Cortelli and Davi Aquino and Chhaju R. Goyal and Pejmon Amini}, title = {Early Benefits with Daily Rinsing on Gingival Health Improvements with an Essential Oil Mouthrinse {\textendash} Post{\textendash}Hoc Analysis of 5 Clinical Trials}, volume = {88}, number = {suppl 1}, pages = {40--50}, year = {2014}, publisher = {American Dental Hygienists{\textquoteright} Association}, abstract = {Purpose: The aim of this investigation through post-hoc analyses was to determine the ability to achieve gingival health in the short term with daily rinsing with an essential oil containing antimicrobial mouthrinse. Methods: Conventional Analysis of Covariance (ANCOVA) on whole mouth mean plaque and gingivitis scores were originally conducted to demonstrate efficacy of adjunctive use of Cool Mint{\textregistered} LISTERINE{\textregistered} Antiseptic (EO) compared to negative control [brushing (B) or brushing/flossing (BF)] in each of 5 studies containing a 4 week evaluation. The Modified Gingival Index (MGI) was split into 2 categories: healthy (scores 0, 1) and unhealthy (>=2). Data, reflecting subjects that completed 4 weeks of treatment from 5 studies, were evaluated to determine the mean percent of healthy sites and mean percent of more inflamed {\textquotedblleft}affected{\textquotedblright} areas (MGI>=3). Results: At baseline, the mean percent healthy gingival sites ranged from 0.1 to 3.2\%. At 4 weeks, up to 29.3\% and 16.1\% of sites were healthy for the EO group and negative control group, respectively. Three and 6 month data from 2 of the 5 studies resulted in up to 39.6\% and 62\% at 3 and 6 month mean percent healthy sites per subject for EO and up to 17.2\% and 15.6\% at 3 and 6 months, respectively, for negative control. Virtually plaque free sites (PI =0, 1) at 4 weeks ranged up to 34.3\% and 8.1\% for EO and control groups, respectively. Conclusion: Significantly more healthy gingival sites and virtually plaque free tooth surfaces can be achieved as early as 4 weeks with use of an essential oil antimicrobial mouthrinse. This finding continues through 6 months twice daily use as part of oral care practices compared to mechanical oral hygiene alone.}, issn = {1553-0205}, URL = {https://jdh.adha.org/content/88/suppl_1/40}, eprint = {https://jdh.adha.org/content/88/suppl_1/40.full.pdf}, journal = {American Dental Hygienists{\textquoteright} Association} }