TY - JOUR T1 - Proliferative verrucous leukoplakia: An aggressive form of oral leukoplakia JF - American Dental Hygienists Association JO - J Dent Hyg SP - 7 LP - 7 VL - 78 IS - 3 AU - Thomas P Shopper AU - Robert B Brannon AU - William H Stalker Y1 - 2004/06/01 UR - http://jdh.adha.org/content/78/3/7.abstract N2 - Proliferative verrucous leukoplakia (PVL) is an aggressive form of oral leukoplakia that is persistent, often multifocal, and refractory to treatment with a high risk of recurrence and malignant transformation. This article describes the clinical aspects and histologic features of a case that demonstrated the typical behavior pattern in a long-standing, persistent lesion of PVL of the mandibular gingiva and that ultimately developed into squamous cell carcinoma. Prognosis is poor for this seemingly harmless-appearing white lesion of the oral mucosa. ER -